Technology Process of Benzoic acid, 2-amino-5-[4-(cyclohexylmethylamino)-4-oxobutoxy]-,
monohydrochloride
There total 7 articles about Benzoic acid, 2-amino-5-[4-(cyclohexylmethylamino)-4-oxobutoxy]-,
monohydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; hydrogen;
palladium on activated charcoal;
In
ethanol;
under 3102.9 Torr;
DOI:10.1021/jm00385a011
- Guidance literature:
-
Multi-step reaction with 3 steps
1: aq. Na2CO3 / tetrahydrofuran / 1 h / Ambient temperature
2: 95 percent / Bu4NMnO4, pyridine / 1 h / Ambient temperature
3: 95 percent / H2, HCl / 10percent Pd/C / ethanol / 3102.9 Torr
With
pyridine; hydrogenchloride; tetra-n-butylammonium permanganate; hydrogen; sodium carbonate;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol;
DOI:10.1021/jm00385a011
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 95 percent / K2CO3 / dimethylformamide / 1 h / 100 °C
2: 96 percent / aq. KOH / ethanol
3: oxalyl chloride / benzene; dimethylformamide / 1 h / Ambient temperature
4: aq. Na2CO3 / tetrahydrofuran / 1 h / Ambient temperature
5: 95 percent / Bu4NMnO4, pyridine / 1 h / Ambient temperature
6: 95 percent / H2, HCl / 10percent Pd/C / ethanol / 3102.9 Torr
With
pyridine; hydrogenchloride; potassium hydroxide; oxalyl dichloride; tetra-n-butylammonium permanganate; hydrogen; sodium carbonate; potassium carbonate;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jm00385a011
