1,2-dimethyl-4-[(E)-2-(2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclo-pentadecin-15-yl)vinyl]pyridinium tosylate

Base Information

• Chemical Name: 1,2-dimethyl-4-[(E)-2-(2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclo-pentadecin-15-yl)vinyl]pyridinium tosylate
• CAS No.: 1338068-46-4
• Molecular Formula: C₇H₇O₃S*C₂₃H₃₀NO₅
• Molecular Weight: 571.692
• Mol file: 1338068-46-4.mol

Synonyms:

Chemical Property of 1,2-dimethyl-4-[(E)-2-(2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclo-pentadecin-15-yl)vinyl]pyridinium tosylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-dimethyl-4-[(E)-2-(2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclo-pentadecin-15-yl)vinyl]pyridinium tosylate

There total 2 articles about 1,2-dimethyl-4-[(E)-2-(2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclo-pentadecin-15-yl)vinyl]pyridinium tosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-lutidine (108-47-4) → 1,2-dimethyl-4-[(E)-2-(2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclo-pentadecin-15-yl)vinyl]pyridinium tosylate (1338068-46-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium tert-butylate / N,N-dimethyl-formamide

2: 2 h / 125 °C

With potassium tert-butylate; In N,N-dimethyl-formamide;

DOI:10.1002/chem.201100998

Reference yield:

benzo-15-crown-5-ether (60835-73-6) → 1,2-dimethyl-4-[(E)-2-(2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclo-pentadecin-15-yl)vinyl]pyridinium tosylate (1338068-46-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium tert-butylate / N,N-dimethyl-formamide

2: 2 h / 125 °C

With potassium tert-butylate; In N,N-dimethyl-formamide;

DOI:10.1002/chem.201100998

Reference yield: 67.0%

4-(1,4-dioxa-7,13-dithia-10-azacyclopentadecan-10-yl) benzaldehyde (240797-82-4) + 1,2-dimethyl-4-[(E)-2-(2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclo-pentadecin-15-yl)vinyl]pyridinium tosylate (1338068-46-4) → C40H53N2O7S2(1+)*ClO4(1-) (1338068-48-6)

Guidance literature:

4-(1,4-dioxa-7,13-dithia-10-azacyclopentadecan-10-yl) benzaldehyde; 1,2-dimethyl-4-[(E)-2-(2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclo-pentadecin-15-yl)vinyl]pyridinium tosylate; With pyrrolidine; In butan-1-ol; for 0.5h; Reflux;

With sodium perchlorate; In methanol;

DOI:10.1002/chem.201100998

upstream raw materials:

2,4-lutidine

benzo-15-crown-5-ether

Downstream raw materials:

C₄₀H₅₃N₂O₇S₂⁽¹⁺⁾*ClO₄^(1-)