C₄₃H₅₀N₆O₆

Base Information

• Chemical Name: C₄₃H₅₀N₆O₆
• CAS No.: 431053-26-8
• Molecular Formula: C₄₃H₅₀N₆O₆
• Molecular Weight: 746.907
• Mol file: 431053-26-8.mol

Synonyms:

Chemical Property of C₄₃H₅₀N₆O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₃H₅₀N₆O₆

There total 13 articles about C₄₃H₅₀N₆O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyridine-2-carbaldehyde (1121-60-4) → C43H50N6O6 (431053-26-8)

Guidance literature:

Multi-step reaction with 9 steps

1: N,N',N'-trimethylenediamine; n-butyllithium / tetrahydrofuran; hexane; cyclohexane

2: sodium chlorite; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene / tert-butyl alcohol; acetonitrile; water

3: caesium carbonate / N,N-dimethyl-formamide

4: 3-chloro-benzenecarboperoxoic acid / dichloromethane

5: bis-triphenylphosphine-palladium(II) chloride; copper(II) oxide / N,N-dimethyl-formamide / 110 °C

6: trifluoroacetic anhydride / N,N-dimethyl-formamide

7: sodium hydroxide; water / tetrahydrofuran

8: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 1-hydroxy-7-aza-benzotriazole / N,N-dimethyl-formamide

9: dimethyl sulfoxide / 100 °C

With dmap; bis-triphenylphosphine-palladium(II) chloride; sodium chlorite; n-butyllithium; 1-hydroxy-7-aza-benzotriazole; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene; water; caesium carbonate; N,N',N'-trimethylenediamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic anhydride; copper(II) oxide; sodium hydroxide; In tetrahydrofuran; hexane; dichloromethane; cyclohexane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;

DOI:10.1016/j.bmcl.2013.06.028

Reference yield:

3-(tributylstannyl)picolinaldehyde (431052-64-1) → C43H50N6O6 (431053-26-8)

Guidance literature:

Multi-step reaction with 8 steps

1: sodium chlorite; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene / tert-butyl alcohol; acetonitrile; water

2: caesium carbonate / N,N-dimethyl-formamide

3: 3-chloro-benzenecarboperoxoic acid / dichloromethane

4: bis-triphenylphosphine-palladium(II) chloride; copper(II) oxide / N,N-dimethyl-formamide / 110 °C

5: trifluoroacetic anhydride / N,N-dimethyl-formamide

6: sodium hydroxide; water / tetrahydrofuran

7: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 1-hydroxy-7-aza-benzotriazole / N,N-dimethyl-formamide

8: dimethyl sulfoxide / 100 °C

With dmap; bis-triphenylphosphine-palladium(II) chloride; sodium chlorite; 1-hydroxy-7-aza-benzotriazole; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene; water; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic anhydride; copper(II) oxide; sodium hydroxide; In tetrahydrofuran; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;

DOI:10.1016/j.bmcl.2013.06.028

Reference yield:

C19H33NO3Sn (431052-65-2) → C43H50N6O6 (431053-26-8)

Guidance literature:

Multi-step reaction with 5 steps

1: bis-triphenylphosphine-palladium(II) chloride; copper(II) oxide / N,N-dimethyl-formamide / 110 °C

2: trifluoroacetic anhydride / N,N-dimethyl-formamide

3: sodium hydroxide; water / tetrahydrofuran

4: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 1-hydroxy-7-aza-benzotriazole / N,N-dimethyl-formamide

5: dimethyl sulfoxide / 100 °C

With dmap; bis-triphenylphosphine-palladium(II) chloride; 1-hydroxy-7-aza-benzotriazole; water; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic anhydride; copper(II) oxide; sodium hydroxide; In tetrahydrofuran; dimethyl sulfoxide; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2013.06.028

upstream raw materials:

pyridine-2-carbaldehyde

3-(tributylstannyl)picolinaldehyde

C₁₉H₃₃NO₃Sn

C₂₃H₂₈N₂O₆

Downstream raw materials:

C₃₀H₃₂N₆O₄