1-[5-(Benzyloxy)-2-bromophenyl]ethan-1-one

Base Information

Chemical Name:1-[5-(Benzyloxy)-2-bromophenyl]ethan-1-one
CAS No.:105805-16-1
Molecular Formula:C15H13BrO2
Molecular Weight:305.171
Hs Code.:
DSSTox Substance ID:DTXSID30556823
Wikidata:Q82438522

Synonyms:105805-16-1;1-[5-(Benzyloxy)-2-bromophenyl]ethan-1-one;SCHEMBL5801964;DTXSID30556823;1-(5-(Benzyloxy)-2-bromophenyl)ethanone

Suppliers and Price of 1-[5-(Benzyloxy)-2-bromophenyl]ethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-[5-(Benzyloxy)-2-bromophenyl]ethan-1-one

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:304.00989
Heavy Atom Count:18
Complexity:274

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=C(C=CC(=C1)OCC2=CC=CC=C2)Br

Technology Process of 1-[5-(Benzyloxy)-2-bromophenyl]ethan-1-one

There total 5 articles about 1-[5-(Benzyloxy)-2-bromophenyl]ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1354364-52-5
1-[5-(benzyloxy)-2-bromophenyl]ethanol

: 105805-16-1
1-[2-bromo-5-(phenylmethoxy)phenyl]ethanone

Guidance literature:: With silica gel; pyridinium chlorochromate; In dichloromethane; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/ol2032625

Reference yield: 86.0%

: 34068-01-4
1-[3-(phenylmethoxy)phenyl]ethan-1-one

: 105805-16-1
1-[2-bromo-5-(phenylmethoxy)phenyl]ethanone

Guidance literature:: With bromine; sodium acetate; In acetic acid; for 24h; Ambient temperature; in the dark;

Reference yield:

: 85604-06-4
5-(benzyloxy)-2-bromobenzaldehyde

: 105805-16-1
1-[2-bromo-5-(phenylmethoxy)phenyl]ethanone

Guidance literature:: Multi-step reaction with 2 steps

1.1: iodine; magnesium / diethyl ether / Inert atmosphere

1.2: 3 h / -10 °C / Inert atmosphere

1.3: Inert atmosphere

2.1: silica gel; pyridinium chlorochromate / dichloromethane / 2 h / 20 °C / Inert atmosphere

With iodine; silica gel; magnesium; pyridinium chlorochromate; In diethyl ether; dichloromethane; 1.2: Grignard reaction;
DOI:10.1021/ol2032625