Technology Process of 1-[5-(Benzyloxy)-2-bromophenyl]ethan-1-one
There total 5 articles about 1-[5-(Benzyloxy)-2-bromophenyl]ethan-1-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
silica gel; pyridinium chlorochromate;
In
dichloromethane;
at 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1021/ol2032625
- Guidance literature:
-
With
bromine; sodium acetate;
In
acetic acid;
for 24h;
Ambient temperature;
in the dark;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: iodine; magnesium / diethyl ether / Inert atmosphere
1.2: 3 h / -10 °C / Inert atmosphere
1.3: Inert atmosphere
2.1: silica gel; pyridinium chlorochromate / dichloromethane / 2 h / 20 °C / Inert atmosphere
With
iodine; silica gel; magnesium; pyridinium chlorochromate;
In
diethyl ether; dichloromethane;
1.2: Grignard reaction;
DOI:10.1021/ol2032625
![1-[5-(benzyloxy)-2-bromophenyl]ethanol](/Databaselist/images/loading.webp)
