6-(4-Chlorophenyl)piperidin-2-one

Base Information

Chemical Name:6-(4-Chlorophenyl)piperidin-2-one
CAS No.:41419-29-8
Molecular Formula:C₁₁H₁₂ClNO
Molecular Weight:209.675
Hs Code.:
DSSTox Substance ID:DTXSID701301022

Synonyms:6-(4-chlorophenyl)piperidin-2-one;41419-29-8;SCHEMBL21009133;DTXSID701301022;6-(4-Chlorophenyl)-2-piperidinone;EN300-216824

Suppliers and Price of 6-(4-Chlorophenyl)piperidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 6-(4-Chlorophenyl)piperidin-2-one

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:209.0607417
Heavy Atom Count:14
Complexity:211

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(NC(=O)C1)C2=CC=C(C=C2)Cl

Technology Process of 6-(4-Chlorophenyl)piperidin-2-one

There total 1 articles about 6-(4-Chlorophenyl)piperidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 41419-29-8
6-(4-Chloro-phenyl)-piperidin-2-one

Guidance literature:: Chlorbenzol, Glutarsaeureanhydrid, AlCl3;

Reference yield: 25.0%

: 41419-29-8
6-(4-Chloro-phenyl)-piperidin-2-one

: 109-70-6
1.3-chlorobromopropane

: 6-(4-Chloro-phenyl)-1-(3-chloro-propyl)-piperidin-2-one

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; for 3h; Ambient temperature;

Reference yield:

: 41419-29-8
6-(4-Chloro-phenyl)-piperidin-2-one

: 109758-29-4
1-[3-(4-Benzhydryl-piperazin-1-yl)-propyl]-6-(4-chloro-phenyl)-piperidin-2-one; compound with oxalic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 25 percent / 80percent NaH / dimethylformamide / 3 h / Ambient temperature

2: 1.) KI, 2.) K₂CO₃ / 1.) isobutylmethylketone, reflux, 30 min, 2.) isobutylmethylketone, 48 h

With sodium hydride; potassium carbonate; potassium iodide; In N,N-dimethyl-formamide;