EGF816 (mesylate)

Base Information

Chemical Name:EGF816 (mesylate)
CAS No.:1508250-72-3
Molecular Formula:(x)CH₄O₃S*C₂₆H₃₁ClN₆O₂
Molecular Weight:591.12
Hs Code.:
Mol file:1508250-72-3.mol

Synonyms:

Suppliers and Price of EGF816 (mesylate)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
EGF816mesylate >98%
1 g
$ 2400.00

DC Chemicals
EGF816mesylate >98%
250 mg
$ 1200.00

DC Chemicals
EGF816mesylate >98%
100 mg
$ 600.00

Crysdot
EGF816mesylate 98+%
10mg
$ 347.00

Crysdot
EGF816mesylate 98+%
5mg
$ 243.00

Crysdot
EGF816mesylate 98+%
50mg
$ 1042.00

Crysdot
EGF816mesylate 98+%
100mg
$ 1459.00

Biorbyt Ltd
EGF816 mesylate
250 mg
$ 1802.00

Biorbyt Ltd
EGF816 mesylate
100 mg
$ 912.90

Total 6 raw suppliers

Chemical Property of EGF816 (mesylate)

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

EGF816mesylate >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of EGF816 (mesylate)

There total 12 articles about EGF816 (mesylate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4021-11-8
2-methylisonicotinic acid

: 1508250-72-3
(R,E)-N-(7-chloro-1-(1-(4-(dimethylamino)but-2-enoyl)azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide mesylate

Guidance literature:: Multi-step reaction with 5 steps

1.1: HATU; triethylamine / dichloromethane / 1 h / 20 °C

1.2: 2.17 h

2.1: hydrogenchloride / methanol; 1,4-dioxane / 7 h / 20 °C

3.1: sodium hydroxide / ethyl acetate

4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 1 h / 20 °C

4.2: 120 h

5.1: acetone / 55 °C

With hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; HATU; sodium hydroxide; In 1,4-dioxane; methanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; acetone;

Reference yield:

: 4021-11-8
2-methylisonicotinic acid

: 1508250-72-3
(R,E)-N-(7-chloro-1-(1-(4-(dimethylamino)but-2-enoyl)azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide mesylate

Guidance literature:: Multi-step reaction with 4 steps

1.1: triethylamine; HATU / dichloromethane / 1 h / 20 °C

1.2: 2 h

2.1: hydrogenchloride / methanol; 1,4-dioxane / 7 h / 20 °C

3.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 1 h / 20 °C

3.2: 120 h

4.1: acetone

With hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; HATU; In 1,4-dioxane; methanol; dichloromethane; N,N-dimethyl-formamide; acetone;