4-Isothiazolecarboxylic acid, 3-Methyl-, Methyl ester

Base Information

Chemical Name:4-Isothiazolecarboxylic acid, 3-Methyl-, Methyl ester
CAS No.:74410-97-2
Molecular Formula:C₆H₇NO₂S
Molecular Weight:157.193
Hs Code.:
Mol file:74410-97-2.mol

Synonyms:

Suppliers and Price of 4-Isothiazolecarboxylic acid, 3-Methyl-, Methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Methyl 3-methylisothiazole-4-carboxylate
500mg
$ 315.00

Crysdot
Methyl3-methylisothiazole-4-carboxylate 97%
1g
$ 356.00

CHESS?
KF000977:3-Methyl-isothiazole-4-carboxylicacidmethylester 98
1 g
$ 336.00

Total 19 raw suppliers

Chemical Property of 4-Isothiazolecarboxylic acid, 3-Methyl-, Methyl ester

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Methyl 3-methylisothiazole-4-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Methyl 3-Methylisothiazole-4-carboxylate is used in preparation of substituted fused pyrimidinamines as PI3 kinase modulators useful in treating cancer.

Technology Process of 4-Isothiazolecarboxylic acid, 3-Methyl-, Methyl ester

There total 11 articles about 4-Isothiazolecarboxylic acid, 3-Methyl-, Methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.5%

: 124413-10-1
methyl 3-amino-2-thioformylisocrotonate

: 74410-97-2
methyl 3-methylisothiazole-4-carboxylate

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In ethanol; at 70 ℃; for 3h;
DOI:10.1039/P19890001241

Reference yield:

: 1420625-84-8
methyl 3-amino-2-thioformylbut-2-enoate

: 74410-97-2
methyl 3-methylisothiazole-4-carboxylate

Guidance literature:: methyl 3-amino-2-thioformylbut-2-enoate; With 3-chloro-benzenecarboperoxoic acid; In ethanol; for 3h; under 760.051 Torr; Reflux;

With sodium hydroxide; In ethanol; water; at 20 ℃; under 760.051 Torr;

Reference yield:

: 14205-39-1
methyl 3-aminocrotonate

: 74410-97-2
methyl 3-methylisothiazole-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: trichlorophosphate / tetrahydrofuran / 0 - 30 °C / 760.05 Torr

1.2: 760.05 Torr

2.1: 3-chloro-benzenecarboperoxoic acid / ethanol / 3 h / 760.05 Torr / Reflux

2.2: 20 °C / 760.05 Torr

With 3-chloro-benzenecarboperoxoic acid; trichlorophosphate; In tetrahydrofuran; ethanol;