C₅₂H₄₇N₃P₂

Base Information

• Chemical Name: C₅₂H₄₇N₃P₂
• CAS No.: 1025922-51-3
• Molecular Formula: C₅₂H₄₇N₃P₂
• Molecular Weight: 775.913
• Mol file: 1025922-51-3.mol

Synonyms:

Chemical Property of C₅₂H₄₇N₃P₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₂H₄₇N₃P₂

There total 5 articles about C₅₂H₄₇N₃P₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-azidobenzaldehyde (16714-25-3) → C52H47N3P2 (1025922-51-3)

Guidance literature:

Multi-step reaction with 5 steps

1: 49 percent / diethyl ether / 1) 0 deg C, 1 h, 2) r.t., 1 h

2: 63 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 24 h

3: hydrazine hydrate / tetrahydrofuran; ethanol / 1) r.t., 16 h, 2) 70 deg C, 8 h

4: MgSO₄ / Ambient temperature; 4 Angstroem molecular sieves

5: 2) NaBH₄ / 1) ether, CH₂Cl₂, r.t, 12 h, 2) CH₂Cl₂, CH₃OH, 0 deg C, 1.5 h

With sodium tetrahydroborate; magnesium sulfate; hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; diethyl ether; ethanol;

DOI:10.1021/jo00059a015

Reference yield:

1-(2-azidophenyl)ethan-1-ol (146954-11-2) → C52H47N3P2 (1025922-51-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 63 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 24 h

2: hydrazine hydrate / tetrahydrofuran; ethanol / 1) r.t., 16 h, 2) 70 deg C, 8 h

3: MgSO₄ / Ambient temperature; 4 Angstroem molecular sieves

4: 2) NaBH₄ / 1) ether, CH₂Cl₂, r.t, 12 h, 2) CH₂Cl₂, CH₃OH, 0 deg C, 1.5 h

With sodium tetrahydroborate; magnesium sulfate; hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol;

DOI:10.1021/jo00059a015

Reference yield:

N-<1-(o-azidophenyl)ethyl>phthalimide (146954-12-3) → C52H47N3P2 (1025922-51-3)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrazine hydrate / tetrahydrofuran; ethanol / 1) r.t., 16 h, 2) 70 deg C, 8 h

2: MgSO₄ / Ambient temperature; 4 Angstroem molecular sieves

3: 2) NaBH₄ / 1) ether, CH₂Cl₂, r.t, 12 h, 2) CH₂Cl₂, CH₃OH, 0 deg C, 1.5 h

With sodium tetrahydroborate; magnesium sulfate; hydrazine hydrate; In tetrahydrofuran; ethanol;

DOI:10.1021/jo00059a015

upstream raw materials:

[(S)-1-(2-Azido-phenyl)-ethyl]-[1-(2-azido-phenyl)-eth-(E)-ylidene]-amine

triphenylphosphine

2-azidobenzaldehyde

1-(2-azidophenyl)ethan-1-ol

Downstream raw materials:

[(S)-1-(2-Azido-phenyl)-ethyl]-[1-(2-azido-phenyl)-eth-(E)-ylidene]-amine