Technology Process of 1-Iodo-3-trimethylsilyl-2-butene
There total 1 articles about 1-Iodo-3-trimethylsilyl-2-butene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Alkohol 17 durch Ueberfuehrung in das Jodid (ueber die Stufe des entspr. Chlorids);
DOI:10.1021/ja00818a071
- Guidance literature:
-
2-methyl-2-cyclohexen-1-one;
With
C37H31O2P; trimethylaluminum;
In
diethyl ether; hexane;
at -30 ℃;
for 2.5h;
Inert atmosphere;
With
N,N,N,N,N,N-hexamethylphosphoric triamide; methyllithium;
In
diethyl ether; hexane;
at -30 ℃;
for 0.333333h;
Inert atmosphere;
C7H15ISi;
In
diethyl ether; hexane;
at -30 - 10 ℃;
for 96h;
stereoselective reaction;
Inert atmosphere;
DOI:10.1021/jacs.5b09198
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: C37H31O2P; trimethylaluminum / diethyl ether; hexane / 2.5 h / -30 °C / Inert atmosphere
1.2: 0.33 h / -30 °C / Inert atmosphere
1.3: 96 h / -30 - 10 °C / Inert atmosphere
2.1: potassium carbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1.33 h / 0 °C / Inert atmosphere
With
C37H31O2P; trimethylaluminum; potassium carbonate; 3-chloro-benzenecarboperoxoic acid;
In
diethyl ether; hexane; dichloromethane;
DOI:10.1021/jacs.5b09198
