2-amino-6-[6-{7-[2-(4-benzyloxyphenyl)-6-[1,8]naphthyridin-2-ylpyrimidin-4-yl][1,8]naphthyridin-2-yl}-2-(4-n-butylphenyl)pyrimidin-4-yl]pyridine-3-carboxaldehyde

Base Information

• Chemical Name: 2-amino-6-[6-{7-[2-(4-benzyloxyphenyl)-6-[1,8]naphthyridin-2-ylpyrimidin-4-yl][1,8]naphthyridin-2-yl}-2-(4-n-butylphenyl)pyrimidin-4-yl]pyridine-3-carboxaldehyde
• CAS No.: 1011806-38-4
• Molecular Formula: C₅₃H₄₀N₁₀O₂
• Molecular Weight: 848.966

Synonyms:

Chemical Property of 2-amino-6-[6-{7-[2-(4-benzyloxyphenyl)-6-[1,8]naphthyridin-2-ylpyrimidin-4-yl][1,8]naphthyridin-2-yl}-2-(4-n-butylphenyl)pyrimidin-4-yl]pyridine-3-carboxaldehyde

Chemical Property:

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MSDS Files:

Useful:

Technology Process of 2-amino-6-[6-{7-[2-(4-benzyloxyphenyl)-6-[1,8]naphthyridin-2-ylpyrimidin-4-yl][1,8]naphthyridin-2-yl}-2-(4-n-butylphenyl)pyrimidin-4-yl]pyridine-3-carboxaldehyde

There total 1 articles about 2-amino-6-[6-{7-[2-(4-benzyloxyphenyl)-6-[1,8]naphthyridin-2-ylpyrimidin-4-yl][1,8]naphthyridin-2-yl}-2-(4-n-butylphenyl)pyrimidin-4-yl]pyridine-3-carboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-[2-(4-benzyloxyphenyl)-6-[1,8]naphthyridin-2-yl-pyrimidin-4-yl]ethyl ketone (442128-55-4) + 4,6-bis(2-amino-3-formylpyridyl)-2-(4-n-butylphenyl)pyrimidine (442128-59-8) → 2-amino-6-[6-{7-[2-(4-benzyloxyphenyl)-6-[1,8]naphthyridin-2-ylpyrimidin-4-yl][1,8]naphthyridin-2-yl}-2-(4-n-butylphenyl)pyrimidin-4-yl]pyridine-3-carboxaldehyde (1011806-38-4)

Guidance literature:

With potassium hydroxide; In methanol; ethanol; for 3h; Heating;

DOI:10.1021/jo702495u

Reference yield:

2-amino-6-[6-{7-[2-(4-benzyloxyphenyl)-6-[1,8]naphthyridin-2-ylpyrimidin-4-yl][1,8]naphthyridin-2-yl}-2-(4-n-butylphenyl)pyrimidin-4-yl]pyridine-3-carboxaldehyde (1011806-38-4) + 1-[6-acetyl-2-(4-n-butylphenyl)-pyrimidin-4-yl]-ethyl ketone (442128-29-2) → C124H92N22O2 (1011806-39-5)

Guidance literature:

With pyridine; potassium hydroxide; In methanol; at 68 - 70 ℃; for 4h;

DOI:10.1021/jo702495u

upstream raw materials:

1-[2-(4-benzyloxyphenyl)-6-[1,8]naphthyridin-2-yl-pyrimidin-4-yl]ethyl ketone

4,6-bis(2-amino-3-formylpyridyl)-2-(4-n-butylphenyl)pyrimidine

Downstream raw materials:

C₁₂₄H₉₂N₂₂O₂

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