(S)-2-{(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-thiopropionylamino)-3-phenyl-propionylamino]-3-methyl-butyrylamino}-3-methyl-butyric acid methyl ester

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Chemical Name:(S)-2-{(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-thiopropionylamino)-3-phenyl-propionylamino]-3-methyl-butyrylamino}-3-methyl-butyric acid methyl ester
CAS No.:206124-00-7
Molecular Formula:C₃₄H₄₈N₄O₆S
Molecular Weight:640.844
Hs Code.:

(S)-2-{(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-thiopropionylamino)-3-phenyl-propionylamino]-3-methyl-butyrylamino}-3-methyl-butyric acid methyl ester

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Chemical Property of (S)-2-{(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-thiopropionylamino)-3-phenyl-propionylamino]-3-methyl-butyrylamino}-3-methyl-butyric acid methyl ester

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Technology Process of (S)-2-{(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-thiopropionylamino)-3-phenyl-propionylamino]-3-methyl-butyrylamino}-3-methyl-butyric acid methyl ester

There total 2 articles about (S)-2-{(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-thiopropionylamino)-3-phenyl-propionylamino]-3-methyl-butyrylamino}-3-methyl-butyric acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 21761-30-8,76969-52-3
L-valyl-L-valine methyl ester

: 138643-95-5
Boc-(L)-Phe-ψ(CSNH)-(L)-Phe-OMe

: 206124-00-7
(S)-2-{(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-thiopropionylamino)-3-phenyl-propionylamino]-3-methyl-butyrylamino}-3-methyl-butyric acid methyl ester

Guidance literature:: With phosphate buffer pH 9; chymotrypsin; In N,N-dimethyl-formamide; for 0.25h; Ambient temperature;
DOI:10.1016/S0960-894X(98)00100-0

Reference yield:

: 13122-89-9
(S)-methyl 2-((S)-2-(tert-butoxycarbonylamino)-3-phenylpropanamido)-3-phenylpropanoate

: 206124-00-7
(S)-2-{(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-thiopropionylamino)-3-phenyl-propionylamino]-3-methyl-butyrylamino}-3-methyl-butyric acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 2,4-bis(4-methoxyphenyl)-2,4-dithioxo-1,3,2,4-dithiadiphosphetane

2: 45 percent / chymotrypsin, phosphate buffer pH 9 / dimethylformamide / 0.25 h / Ambient temperature

With Lawessons reagent; phosphate buffer pH 9; chymotrypsin; In N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(98)00100-0