Technology Process of 3-amino-1-benzylpyrid-2-one
There total 5 articles about 3-amino-1-benzylpyrid-2-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 89 percent / pyridine / toluene / 1 h / Heating
2: 89 percent / NH4Cl, polyphosphoric acid / 12 h / 180 °C
3: 50percent aq. KOH / tributylbenzylammonium chloride / toluene / ice-water bath, 2 h, then r.t., 16 h
4: conc. aq. ammonia, CuCl / 1 h / 180 °C / pressure vessel
With
pyridine; potassium hydroxide; ammonium hydroxide; PPA; ammonium chloride; copper(l) chloride;
benzyltri(n-butyl)ammonium chloride;
In
toluene;
DOI:10.1002/jhet.5570200535
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 50percent aq. KOH / tributylbenzylammonium chloride / toluene / ice-water bath, 2 h, then r.t., 16 h
2: conc. aq. ammonia, CuCl / 1 h / 180 °C / pressure vessel
With
potassium hydroxide; ammonium hydroxide; copper(l) chloride;
benzyltri(n-butyl)ammonium chloride;
In
toluene;
DOI:10.1002/jhet.5570200535
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 89 percent / NH4Cl, polyphosphoric acid / 12 h / 180 °C
2: 50percent aq. KOH / tributylbenzylammonium chloride / toluene / ice-water bath, 2 h, then r.t., 16 h
3: conc. aq. ammonia, CuCl / 1 h / 180 °C / pressure vessel
With
potassium hydroxide; ammonium hydroxide; PPA; ammonium chloride; copper(l) chloride;
benzyltri(n-butyl)ammonium chloride;
In
toluene;
DOI:10.1002/jhet.5570200535
