3-(6-catechol-4-yl-1Hpyrazolo[5,1-c][1,2,4]triazol-3-yl)-1-cyclopropyl-6-fluoro-7-(4-ethylpiperazin-1-yl)-quinolin-4(1H)-one hydrochloride

Base Information

Chemical Name:3-(6-catechol-4-yl-1Hpyrazolo[5,1-c][1,2,4]triazol-3-yl)-1-cyclopropyl-6-fluoro-7-(4-ethylpiperazin-1-yl)-quinolin-4(1H)-one hydrochloride
CAS No.:1309961-96-3
Molecular Formula:C₂₈H₂₈FN₇O₃*ClH
Molecular Weight:566.035
Hs Code.:

3-(6-catechol-4-yl-1Hpyrazolo[5,1-c][1,2,4]triazol-3-yl)-1-cyclopropyl-6-fluoro-7-(4-ethylpiperazin-1-yl)-quinolin-4(1H)-one hydrochloride

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Chemical Property of 3-(6-catechol-4-yl-1Hpyrazolo[5,1-c][1,2,4]triazol-3-yl)-1-cyclopropyl-6-fluoro-7-(4-ethylpiperazin-1-yl)-quinolin-4(1H)-one hydrochloride

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Technology Process of 3-(6-catechol-4-yl-1Hpyrazolo[5,1-c][1,2,4]triazol-3-yl)-1-cyclopropyl-6-fluoro-7-(4-ethylpiperazin-1-yl)-quinolin-4(1H)-one hydrochloride

There total 5 articles about 3-(6-catechol-4-yl-1Hpyrazolo[5,1-c][1,2,4]triazol-3-yl)-1-cyclopropyl-6-fluoro-7-(4-ethylpiperazin-1-yl)-quinolin-4(1H)-one hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1215036-45-5
3-(1-amino-5-mercapto-1H-[1,3,4]triazol-2-yl)-1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4(1H)quinolinone

: 1309961-96-3
3-(6-catechol-4-yl-1Hpyrazolo[5,1-c][1,2,4]triazol-3-yl)-1-cyclopropyl-6-fluoro-7-(4-ethylpiperazin-1-yl)-quinolin-4(1H)-one hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydroxide / ethanol; water / 12 h / 20 °C

2: hydrogenchloride / ethanol; water / 6 h / Reflux

3: 1 h / Reflux

4: hydrogenchloride / water; acetic acid / 3 h / Reflux

With hydrogenchloride; sodium hydroxide; In ethanol; water; acetic acid;
DOI:10.1016/j.cclet.2011.01.018

Reference yield:

: C₂₈H₃₀FN₇O₄S

: 1309961-96-3
3-(6-catechol-4-yl-1Hpyrazolo[5,1-c][1,2,4]triazol-3-yl)-1-cyclopropyl-6-fluoro-7-(4-ethylpiperazin-1-yl)-quinolin-4(1H)-one hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / ethanol; water / 6 h / Reflux

2: 1 h / Reflux

3: hydrogenchloride / water; acetic acid / 3 h / Reflux

With hydrogenchloride; In ethanol; water; acetic acid;
DOI:10.1016/j.cclet.2011.01.018

Reference yield:

: 1309961-91-8
C₂₈H₂₈FN₇O₃S*ClH

: 1309961-96-3
3-(6-catechol-4-yl-1Hpyrazolo[5,1-c][1,2,4]triazol-3-yl)-1-cyclopropyl-6-fluoro-7-(4-ethylpiperazin-1-yl)-quinolin-4(1H)-one hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 1 h / Reflux

2: hydrogenchloride / water; acetic acid / 3 h / Reflux

With hydrogenchloride; In water; acetic acid;
DOI:10.1016/j.cclet.2011.01.018