benzene-1,2-diylbis[(4-methoxyphenyl)methanone]

Base Information

• Chemical Name: benzene-1,2-diylbis[(4-methoxyphenyl)methanone]
• CAS No.: 7477-28-3
• Molecular Formula: C22H18 O4
• Molecular Weight: 346.383
• Mol file: 7477-28-3.mol

Synonyms:Benzene,o-di-p-anisoyl- (8CI); Methanone, 1,2-phenylenebis[(4-methoxyphenyl)- (9CI);NSC 400809

Chemical Property of benzene-1,2-diylbis[(4-methoxyphenyl)methanone]

Chemical Property:

• Vapor Pressure: 5.02E-12mmHg at 25°C
• Boiling Point: 547.1°C at 760 mmHg
• Flash Point: 240.5°C
• Density: 1.179g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of benzene-1,2-diylbis[(4-methoxyphenyl)methanone]

There total 20 articles about benzene-1,2-diylbis[(4-methoxyphenyl)methanone] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

C24H22O2 (1385794-37-5) → C24H22O4 + o-bis(p-methoxyphenoyl)benzene (7477-28-3)

Guidance literature:

With biphenyl; 9,10-Dicyanoanthracene; oxygen; In acetonitrile; at 20 ℃; for 0.166667h; Reagent/catalyst; Irradiation;

DOI:10.1007/s11164-012-0637-3

Reference yield: 54.0%

1,3-Bis(4-methoxyphenyl)benzothiophen (128709-98-8) → o-bis(p-methoxyphenoyl)benzene (7477-28-3) + (E)-4'-Methoxy-2-(4-methoxythiobenzoyl)benzophenon-S-oxid (128709-99-9)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; for 24h; Ambient temperature;

Reference yield: 25.0%

1-bromo-4-methoxy-benzene (104-92-7) + benzene-1,2-dicarbothioic acid di(S-pyridin-2-yl) ester (162339-29-9) → o-bis(p-methoxyphenoyl)benzene (7477-28-3)

Guidance literature:

1-bromo-4-methoxy-benzene; With magnesium; In tetrahydrofuran; at 30 ℃; for 3.5h;

benzene-1,2-dicarbothioic acid di(S-pyridin-2-yl) ester; In tetrahydrofuran; at 0 ℃; for 0.25h; Further stages.;

DOI:10.1016/j.jorganchem.2006.08.049

upstream raw materials:

phthalic anhydride

(4-methoxyphenyl)magnesium iodide

diethyl ether

benzene

Downstream raw materials:

1,2-bis-(α-hydroxy-4-methoxy-benzyl)-benzene

1,4-bis-(4-methoxy-phenyl)-phthalazine

1,2-bis-(4-hydroxy-benzoyl)-benzene

1,2-bis-(α-hydroxyimino-4-methoxy-benzyl)-benzene