1-ferrocenyl-4-methyl-3-([4-nitrophenyl]ethynyl)pent-3-en-1-yne

Base Information

• Chemical Name: 1-ferrocenyl-4-methyl-3-([4-nitrophenyl]ethynyl)pent-3-en-1-yne
• CAS No.: 944469-35-6
• Molecular Formula: C₂₄H₁₉FeNO₂
• Molecular Weight: 409.267
• Mol file: 944469-35-6.mol

Synonyms:

Chemical Property of 1-ferrocenyl-4-methyl-3-([4-nitrophenyl]ethynyl)pent-3-en-1-yne

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-ferrocenyl-4-methyl-3-([4-nitrophenyl]ethynyl)pent-3-en-1-yne

There total 1 articles about 1-ferrocenyl-4-methyl-3-([4-nitrophenyl]ethynyl)pent-3-en-1-yne which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

p-nitrobenzene iodide (636-98-6) + 4-methyl-3-(ferrocenylethynyl)-1-(trimethylsilyl)pent-3-en-1-yne (944469-33-4) → 1-ferrocenyl-4-methyl-3-([4-nitrophenyl]ethynyl)pent-3-en-1-yne (944469-35-6)

Guidance literature:

With catalyst: PdCl₂(P(C₆H₅)2, CuI, isopropylamine; K₂CO₃; In tetrahydrofuran; methanol; water; a mixt. of silylalkyne and K2CO3 in wet THF and CH3OH was stirred at room temp. up to 2 h, (C2H5)2O and satd. aq. NH4Cl were added, washed with aq. NH4Cl, dried, concd., amine was added, THF, Pd-complex and amine, after 5 min CuI was added, 1.5 h; diethyl ether and H2O were added, the organic phase was sepd., washed with satd. aq. NH4Cl, dried, concd., flash column chromy. on silica gel (hexane/diethyl ether 5:1);

DOI:10.1002/hlca.200790092

upstream raw materials:

p-nitrobenzene iodide

4-methyl-3-(ferrocenylethynyl)-1-(trimethylsilyl)pent-3-en-1-yne