BF₄^(1-)*C₁₇H₁₇F₅N₃⁽¹⁺⁾

Base Information

• Chemical Name: BF₄^(1-)*C₁₇H₁₇F₅N₃⁽¹⁺⁾
• CAS No.: 1318249-54-5
• Molecular Formula: BF₄*C₁₇H₁₇F₅N₃
• Molecular Weight: 445.139
• Mol file: 1318249-54-5.mol

Synonyms:

Chemical Property of BF₄^(1-)*C₁₇H₁₇F₅N₃⁽¹⁺⁾

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of BF₄^(1-)*C₁₇H₁₇F₅N₃⁽¹⁺⁾

There total 6 articles about BF₄^(1-)*C₁₇H₁₇F₅N₃⁽¹⁺⁾ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C16H18F5N3 + orthoformic acid triethyl ester (122-51-0) → BF4(1-)*C17H17F5N3(1+) (1318249-54-5)

Guidance literature:

C₁₆H₁₈F₅N₃; orthoformic acid triethyl ester; In chlorobenzene; at 130 ℃; for 23h;

With tetrafluoroboric acid; In chlorobenzene; at 120 ℃; for 12h;

DOI:10.1021/ja205714g

Reference yield:

C19H29NO7 (1318249-50-1) → BF4(1-)*C17H17F5N3(1+) (1318249-54-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium tetrahydroborate; acetic acid / dichloromethane / 3 h / 0 °C

2.1: toluene / 5 h / 110 °C

3.1: trifluoroacetic acid / dichloromethane / 4 h

4.1: trimethoxonium tetrafluoroborate / dichloromethane / 12 h / 20 °C

4.2: 24 h / 20 °C

5.1: chlorobenzene / 23 h / 130 °C

5.2: 12 h / 120 °C

With sodium tetrahydroborate; trimethoxonium tetrafluoroborate; acetic acid; trifluoroacetic acid; In dichloromethane; chlorobenzene; toluene;

DOI:10.1021/ja205714g

Reference yield:

(R)-tert-butyl 2-cyclohexyl-5-oxopyrrolidine-1-carboxylate (1012369-67-3) → BF4(1-)*C17H17F5N3(1+) (1318249-54-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: trifluoroacetic acid / dichloromethane / 4 h

2.1: trimethoxonium tetrafluoroborate / dichloromethane / 12 h / 20 °C

2.2: 24 h / 20 °C

3.1: chlorobenzene / 23 h / 130 °C

3.2: 12 h / 120 °C

With trimethoxonium tetrafluoroborate; trifluoroacetic acid; In dichloromethane; chlorobenzene;

DOI:10.1021/ja205714g

upstream raw materials:

(R)-tert-butyl 2-cyclohexyl-5-oxopyrrolidine-1-carboxylate

C₁₉H₂₉NO₇

C₁₉H₃₁NO₆

(R)-5-cyclohexylpyrrolidin-2-one

Refernces