Technology Process of 5-(bromomethyl)-1,2-dichloro-3-iodobenzene
There total 5 articles about 5-(bromomethyl)-1,2-dichloro-3-iodobenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-Bromosuccinimide; dibenzoyl peroxide;
In
tetrachloromethane;
for 10h;
Reflux;
DOI:10.1016/j.bmc.2009.07.021
- Guidance literature:
-
Multi-step reaction with 4 steps
1: tert.-butylnitrite; copper dichloride / acetonitrile / 1.5 h / 65 °C
2: hydrogenchloride; iron / ethanol; water / 1.5 h / Reflux
3: sulfuric acid; sodium nitrite / acetic acid / 25 - 75 °C
4: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 10 h / Reflux
With
hydrogenchloride; N-Bromosuccinimide; tert.-butylnitrite; sulfuric acid; iron; copper dichloride; sodium nitrite; dibenzoyl peroxide;
In
tetrachloromethane; ethanol; water; acetic acid; acetonitrile;
1: Sandmeyer reaction;
DOI:10.1016/j.bmc.2009.07.021
- Guidance literature:
-
Multi-step reaction with 3 steps
1: hydrogenchloride; iron / ethanol; water / 1.5 h / Reflux
2: sulfuric acid; sodium nitrite / acetic acid / 25 - 75 °C
3: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 10 h / Reflux
With
hydrogenchloride; N-Bromosuccinimide; sulfuric acid; iron; sodium nitrite; dibenzoyl peroxide;
In
tetrachloromethane; ethanol; water; acetic acid;
DOI:10.1016/j.bmc.2009.07.021
