<2,2-(2)H2>-phenyacetic acid

Base Information

• Chemical Name: <2,2-(2)H2>-phenyacetic acid
• CAS No.: 144899-74-1
• Molecular Formula: C₈H₈O₂
• Molecular Weight: 139.126
• Mol file: 144899-74-1.mol

Synonyms:

Chemical Property of <2,2-(2)H2>-phenyacetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <2,2-(2)H2>-phenyacetic acid

There total 2 articles about <2,2-(2)H2>-phenyacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C9H5(2)H3O4 (144899-73-0) → <2,2-(2)H2>-phenyacetic acid (144899-74-1)

Guidance literature:

at 180 ℃;

DOI:10.1039/P29800000579

Reference yield:

phenylmalonic acid (2613-89-0) → <2,2-(2)H2>-phenyacetic acid (144899-74-1)

Guidance literature:

Multi-step reaction with 2 steps

1: D₂O / dioxane / 24 h / 30 °C

2: 85 percent / 180 °C

With water-d2; In 1,4-dioxane;

DOI:10.1039/P29800000579

Reference yield:

<2,2-(2)H2>-phenyacetic acid (144899-74-1) → C11H12(2)HN (74157-82-7)

Guidance literature:

Multi-step reaction with 2 steps

1: DCC-HBT / tetrahydrofuran / 24 h

2: NEt₃

With triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran;

DOI:10.1039/P29800000579

upstream raw materials:

C₉H₅⁽²⁾H₃O₄

phenylmalonic acid

Downstream raw materials:

N-isopropyl-2-phenyl<2,2-(2)H2>acetamide

C₁₁H₁₂⁽²⁾HN