4-[2-(2-Methylpropylamino)ethylsulfonyl]benzenesulfonamide

Base Information

Chemical Name:4-[2-(2-Methylpropylamino)ethylsulfonyl]benzenesulfonamide
CAS No.:135832-44-9
Molecular Formula:C₁₂H₂₀N₂O₄S₂
Molecular Weight:320.434
Hs Code.:
DSSTox Substance ID:DTXSID20872241
Nikkaji Number:J459.526B

Synonyms:135832-44-9;DTXSID20872241;4-{2-[(2-Methylpropyl)amino]ethanesulfonyl}benzene-1-sulfonamide

Suppliers and Price of 4-[2-(2-Methylpropylamino)ethylsulfonyl]benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[2-(2-Methylpropylamino)ethylsulfonyl]benzenesulfonamide

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:320.08644947
Heavy Atom Count:20
Complexity:481

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)CNCCS(=O)(=O)C1=CC=C(C=C1)S(=O)(=O)N

Technology Process of 4-[2-(2-Methylpropylamino)ethylsulfonyl]benzenesulfonamide

There total 6 articles about 4-[2-(2-Methylpropylamino)ethylsulfonyl]benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 701-34-8
4-bromo-benzenesulfonic acid amide

: 135832-44-9
4-<<2-(isobutylamino)ethyl>sulfonyl>benzenesulfonamide

Guidance literature:: Multi-step reaction with 6 steps

1: 34.4 g / acetonitrile / 1 h

2: dimethylformamide / 1 h / Heating

3: 10percent aq. NaOH / methanol / 1 h / Heating

4: Oxone / H₂O / 18 h

5: p-toluenesulfonyl chloride, pyridine / 2 h / 0 - 5 °C

6: pyridine / 18 h / Heating

With pyridine; Oxone; sodium hydroxide; p-toluenesulfonyl chloride; In methanol; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm00114a020

Reference yield:

: 29619-31-6
N,N-dimethyl-N'-<(4-bromophenyl)sulfonyl>formamidine

: 135832-44-9
4-<<2-(isobutylamino)ethyl>sulfonyl>benzenesulfonamide

Guidance literature:: Multi-step reaction with 5 steps

1: dimethylformamide / 1 h / Heating

2: 10percent aq. NaOH / methanol / 1 h / Heating

3: Oxone / H₂O / 18 h

4: p-toluenesulfonyl chloride, pyridine / 2 h / 0 - 5 °C

5: pyridine / 18 h / Heating

With pyridine; Oxone; sodium hydroxide; p-toluenesulfonyl chloride; In methanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00114a020

Reference yield:

: 108966-48-9
4-((2-hydroxyethyl)thio)benzenesulfonamide

: 135832-44-9
4-<<2-(isobutylamino)ethyl>sulfonyl>benzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: Oxone / H₂O / 18 h

2: p-toluenesulfonyl chloride, pyridine / 2 h / 0 - 5 °C

3: pyridine / 18 h / Heating

With pyridine; Oxone; p-toluenesulfonyl chloride; In water;
DOI:10.1021/jm00114a020