701-34-8

Basic information

• Product Name: 4-Bromobenzenesulfonamide
• Synonyms: 4-Bromobenzenesulfonamide, 97+%;4-BroMobenzenesulfonaMide >=99.0% (T);P-BROMOBENZENESULFONAMIDE;Benzenesulfonamide, 4-bromo-;Benzenesulfonamide, p-bromo-;p-bromo-benzenesulfonamid;AKOS 206-12;4-BROMOBENZENESULPHONAMIDE
• CAS NO: 701-34-8
• Molecular Formula: C₆H₆BrNO₂S
• Molecular Weight: 236.09
• EINECS: -0
• Product Categories: Aryl;Halogenated;Organohalides;blocks;Bromides;Sulfonamides
• Mol File: 701-34-8.mol
• Article Data: 54

Chemical Properties

• Melting Point: 163-167 °C
• Boiling Point: 360.7°C (rough estimate)
• Flash Point: 171.9 °C
• Appearance: /
• Density: 1.8000 (estimate)
• Vapor Pressure: 7.57E-06mmHg at 25°C
• Refractive Index: 1.6140 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 9.89±0.10(Predicted)
• Water Solubility: 991.6mg/L(15 oC)
• BRN: 2691657
• CAS DataBase Reference: 4-Bromobenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromobenzenesulfonamide(701-34-8)
• EPA Substance Registry System: 4-Bromobenzenesulfonamide(701-34-8)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22
• Safety Statements: 22-24/25
• WGK Germany: 3
• RTECS: DB0550000
• HazardClass: IRRITANT
• Hazardous Substances Data: 701-34-8(Hazardous Substances Data)

Usage

Uses

4-Bromobenzenesulfonamide was used as reagent in preparation of cobalt(III) complexes of N,R-sulfonyldithiocarbimate anion. It was also used in the synthesis of 2-, 3- and 4-(substituted-phenylethynyl)benzenesulfonamides.

General Description

4-Bromobenzenesulfonamide is a metabolite of ebrotidine, a new H2-receptor antagonist.

InChI:InChI=1/C6H6BrNO2S/c7-5-2-1-3-6(4-5)11(8,9)10/h1-4H,(H2,8,9,10)

Upstream product

• 98-58-8 4-bromobenzenesulfonyl chloride 
• 6647-76-3 p-bromobenzenesulfonyl azide 
• 71-43-2 benzene 
• 7664-93-9 sulfuric acid 
• 500730-57-4 4-bromo-N-(2-hydroxy-2-methylpropyl)-benzenesulfonamide 
• 10035-10-6 hydrogen bromide 
• 63-74-1 sulfanilamide 
• 28122-76-1 acetyl 4-bromo-thiophenolate 
• 673-40-5 4-bromobenzenediazonium tetrafluoroborate 
• 35377-38-9 Tri(p-sulfamoylphenyl)bismutan 
• 108-86-1 bromobenzene 
• 17151-49-4 (4-bromophenyl)tri-n-butylstannane 
• 90944-62-0 N,N-diethyl-4-bromobenzenesulfonamide 
• 93281-65-3 4-bromo-(N-tert-butyl)benzenesulfonamide 

Downstream Products

• 7511-56-0 4-bromo-benzenesulfonic acid xanthen-9-ylamide 
• 98590-45-5 (4-bromo-benzenesulfonyl)-oxalamic acid methyl ester 
• 14067-99-3 N-((4-bromophenyl)sulfonyl)benzamide 
• 98273-63-3 (4-bromo-benzenesulfonyl)-formyl-amine 
• 1836-19-7 N,N-dichloro(p-BrC₆H₄)sulfonamide 
• 138-41-0 4-(aminosulfonyl)-benzoic acid 
• 74756-45-9 N,N-dibromo-4-bromobenzenesulfonamide 
• 98950-00-6 4-bromo-N-(2,3-dihydroxypropyl)benzenesulfonamide 
• 105208-51-3 4-bromo-benzenesulfonic acid-[bis-(2,3-dihydroxy-propyl)-amide] 
• 27715-57-7 N-(4-bromo-benzenesulfonyl)-phthalimide 
• 100874-17-7 3-(4-bromo-benzenesulfonylamino)-phthalide 
• 1156-18-9 di(4-bromobenzenesulfonyl)amine 
• 19876-04-1 N-(4-bromo-benzenesulfonyl)-N'-butyl-urea 
• 27064-13-7 N-p-Bromphenylsulfonyltrichlorophosphazoiminotrichloracetyl 

Relevant articles and documents

Unlocking Amides through Selective C–N Bond Cleavage: Allyl Bromide-Mediated Divergent Synthesis of Nitrogen-Containing Functional Groups

We report a new set of reactions based on the unlocking of amides through simple treatment with allyl bromide, creating a common platform for accessing a diverse range of nitrogen-containing functional groups such as primary amides, sulfonamides, primary amines, N-acyl compounds (esters, thioesters, amides), and N-sulfonyl esters. The method has potential industrial applicability, as demonstrated through gram-scale syntheses in batch and in a continuous flow system.

METHOD FOR PRODUCING OXIDE USING BETA-MANGANESE DIOXIDE

With the object of efficiently producing an oxidation product, the present invention provides a method for producing an oxidation product by oxidizing a raw material compound in the presence of oxygen, wherein the raw material compound is oxidized in the presence of manganese dioxide having a crystal structure of β-type.

NAPHTHYRIDINE DERIVATIVES AS PRC2 INHIBITORS

Disclosed are compounds of formula (I) or (II) that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.