(-)-(E)-10-Hydroxy-Amitriptylline

Base Information

• Chemical Name: (-)-(E)-10-Hydroxy-Amitriptylline
• CAS No.: 129312-48-7
• Molecular Formula: C₂₀H₂₃NO
• Molecular Weight: 293.409
• Mol file: 129312-48-7.mol

Synonyms:

Chemical Property of (-)-(E)-10-Hydroxy-Amitriptylline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (-)-(E)-10-Hydroxy-Amitriptylline

There total 1 articles about (-)-(E)-10-Hydroxy-Amitriptylline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

amitryptyline (50-48-6) → 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine (72-69-5) + (Z)-N,N-dimethyl-3-(10,11-dihydro-10-hydroxy-5H-dibenzocycloheptene)-Δ5,γ-propylamine (1159-82-6) + (-)-(E)-10-Hydroxy-Amitriptylline (64520-05-4,129312-48-7,129312-49-8)

Guidance literature:

With glucose-6-phosphate dehydrogenase; Tris-HCl buffer; α-D-glucose 6-phosphate; liver microsomes of Wistar rats; NADPH; magnesium chloride; In water; at 37 ℃; Rate constant; Product distribution;

DOI:10.1111/j.2042-7158.1996.tb06003.x

upstream raw materials:

amitryptyline