di-tert-butyl 1-(bicyclo[1.1.1]pentan-1-yl)hydrazine-1,2-dicarboxylate

Base Information

• Chemical Name: di-tert-butyl 1-(bicyclo[1.1.1]pentan-1-yl)hydrazine-1,2-dicarboxylate
• CAS No.: 1326242-72-1
• Molecular Formula: C₁₅H₂₆N₂O₄
• Molecular Weight: 298.382
• Mol file: 1326242-72-1.mol

Synonyms:

Chemical Property of di-tert-butyl 1-(bicyclo[1.1.1]pentan-1-yl)hydrazine-1,2-dicarboxylate

Chemical Property:

• Melting Point: 135 °C (decomp)
• PKA: 8.94±0.20(Predicted)
• Density: 1.14±0.1 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

Di-tert-butyl1-(bicyclo[1.1.1]pentan-1-yl)hydrazine-1,2-dicarboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of di-tert-butyl 1-(bicyclo[1.1.1]pentan-1-yl)hydrazine-1,2-dicarboxylate

There total 3 articles about di-tert-butyl 1-(bicyclo[1.1.1]pentan-1-yl)hydrazine-1,2-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

di-tert-butyl-diazodicarboxylate (870-50-8) + [1.1.1]propellane (35634-10-7) → di-tert-butyl 1-(bicyclo[1.1.1]pentan-1-yl)hydrazine-1,2-dicarboxylate (1326242-72-1)

Guidance literature:

With tris(2,2,6,6-tetramethyl-3,5-heptanedionato) manganese (III); phenylsilane; In diethyl ether; dichloromethane; isopropyl alcohol; pentane; at 0 ℃; for 21h; Inert atmosphere;

DOI:10.1021/ol201883z

Reference yield: 29.0%

bicyclo[1.1.1]pentane (311-75-1) + di-tert-butyl (E)-azodicarboxylate (870-50-8) → di-tert-butyl 1-(bicyclo[1.1.1]pentan-1-yl)hydrazine-1,2-dicarboxylate (1326242-72-1)

Guidance literature:

With manganese(III) (Z)-2,2,6,6-tetramethyl-5-oxohept-3-en-3-olate; In isopropyl alcohol; at -15 - 20 ℃; for 24.5h;

Reference yield:

1,1-bis(chloromethyl)-2,2-dibromocyclopropane (98577-44-7) → di-tert-butyl 1-(bicyclo[1.1.1]pentan-1-yl)hydrazine-1,2-dicarboxylate (1326242-72-1)

Guidance literature:

Multi-step reaction with 2 steps

1: pentane

2: manganese(III) (Z)-2,2,6,6-tetramethyl-5-oxohept-3-en-3-olate / isopropyl alcohol / 24.5 h / -15 - 20 °C

With manganese(III) (Z)-2,2,6,6-tetramethyl-5-oxohept-3-en-3-olate; In isopropyl alcohol; pentane;

upstream raw materials:

di-tert-butyl-diazodicarboxylate

[1.1.1]propellane

bicyclo[1.1.1]pentane

di-tert-butyl (E)-azodicarboxylate