alpha-[2-[4-(1,1-Dimethylethyl)-1-hydroxycyclohexyl]ethynyl]-3-methoxybenzenemethanol

Base Information

Chemical Name:alpha-[2-[4-(1,1-Dimethylethyl)-1-hydroxycyclohexyl]ethynyl]-3-methoxybenzenemethanol
CAS No.:136121-33-0
Molecular Formula:C₂₀H₂₈O₃
Molecular Weight:316.441
Hs Code.:
DSSTox Substance ID:DTXSID701132756
Nikkaji Number:J405.503I

Synonyms:DTXSID701132756;136121-33-0

Suppliers and Price of alpha-[2-[4-(1,1-Dimethylethyl)-1-hydroxycyclohexyl]ethynyl]-3-methoxybenzenemethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of alpha-[2-[4-(1,1-Dimethylethyl)-1-hydroxycyclohexyl]ethynyl]-3-methoxybenzenemethanol

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:316.20384475
Heavy Atom Count:23
Complexity:443

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C1CCC(CC1)(C#CC(C2=CC(=CC=C2)OC)O)O

Technology Process of alpha-[2-[4-(1,1-Dimethylethyl)-1-hydroxycyclohexyl]ethynyl]-3-methoxybenzenemethanol

There total 3 articles about alpha-[2-[4-(1,1-Dimethylethyl)-1-hydroxycyclohexyl]ethynyl]-3-methoxybenzenemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 159763-13-0
1-<1-chloro-1-(p-tolylsulfinyl)ethyl>-4-tert-butyl-1-cyclohexanol

: 136121-33-0
1-<3-Hydroxy-3-(3-methoxyphenyl)-1-propynyl>-4-t-butyl-1-cyclohexanol

Guidance literature:: Multi-step reaction with 2 steps

1: xylene / 0.33 h / Heating

2: 1.) n-BuLi / 1.) THF, 1 h, 2.) -15 deg C

With n-butyllithium; In xylene;
DOI:10.1246/bcsj.64.2153

Reference yield:

: 98-53-3
4-tercbutyl-cyclohexanone

: 136121-33-0
1-<3-Hydroxy-3-(3-methoxyphenyl)-1-propynyl>-4-t-butyl-1-cyclohexanol

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) LDA / 1.) THF

2: xylene / 0.33 h / Heating

3: 1.) n-BuLi / 1.) THF, 1 h, 2.) -15 deg C

With n-butyllithium; lithium diisopropyl amide; In xylene;
DOI:10.1246/bcsj.64.2153