4'-trifluoromethyl-biphenyl-4-sulfonic acid benzoylamide

Base Information

• Chemical Name: 4'-trifluoromethyl-biphenyl-4-sulfonic acid benzoylamide
• CAS No.: 1356496-11-1
• Molecular Formula: C₂₀H₁₄F₃NO₃S
• Molecular Weight: 405.397
• Mol file: 1356496-11-1.mol

Synonyms:

Chemical Property of 4'-trifluoromethyl-biphenyl-4-sulfonic acid benzoylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4'-trifluoromethyl-biphenyl-4-sulfonic acid benzoylamide

There total 2 articles about 4'-trifluoromethyl-biphenyl-4-sulfonic acid benzoylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thiobenzoic acid S-(9H-fluoren-9-ylmethyl) ester (1356496-19-9) → 4'-trifluoromethyl-biphenyl-4-sulfonic acid benzoylamide (1356496-11-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 0.02 h / 20 °C / Inert atmosphere

2: N,N-dimethyl-formamide / 0.02 h / 20 °C / Inert atmosphere

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide;

DOI:10.1039/c1cc14724b

Reference yield:

thiobenzoic acid (98-91-9) + 4'-trifluoromethylbiphenyl-4-sulfonamide (950500-72-8) → 4'-trifluoromethyl-biphenyl-4-sulfonic acid benzoylamide (1356496-11-1)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 0.0166667h; chemoselective reaction; Inert atmosphere;

DOI:10.1039/c1cc14724b

upstream raw materials:

thiobenzoic acid

4'-trifluoromethylbiphenyl-4-sulfonamide

thiobenzoic acid S-(9H-fluoren-9-ylmethyl) ester