4'-(TRIFLUOROMETHYL)-4-BIPHENYLSULFONAMIDE

Base Information

• Chemical Name: 4'-(TRIFLUOROMETHYL)-4-BIPHENYLSULFONAMIDE
• CAS No.: 950500-72-8
• Molecular Formula: C₁₃H₁₀F₃NO₂S
• Molecular Weight: 301.289
• Mol file: 950500-72-8.mol

Synonyms:4'-(TRIFLUOROMETHYL)-4-BIPHENYLSULFONAMIDE

Chemical Property of 4'-(TRIFLUOROMETHYL)-4-BIPHENYLSULFONAMIDE

Chemical Property:

• Vapor Pressure: 5.92E-07mmHg at 25°C
• Boiling Point: 410.7°C at 760 mmHg
• Flash Point: 202.2°C
• PSA: 68.54000
• Density: 1.387g/cm³
• LogP: 4.80090

Purity/Quality:

99%min ^*data from raw suppliers

4'-(TRIFLUOROMETHYL)-4-BIPHENYLSULFONAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4'-(TRIFLUOROMETHYL)-4-BIPHENYLSULFONAMIDE

There total 1 articles about 4'-(TRIFLUOROMETHYL)-4-BIPHENYLSULFONAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

4-bromo-benzenesulfonic acid amide (701-34-8) + 4-trifluoromethylphenylboronic acid (128796-39-4) → 4'-trifluoromethylbiphenyl-4-sulfonamide (950500-72-8)

Guidance literature:

With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 100 ℃; for 17h;

DOI:10.1021/jm070435y

Reference yield:

thiobenzoic acid (98-91-9) + 4'-trifluoromethylbiphenyl-4-sulfonamide (950500-72-8) → 4'-trifluoromethyl-biphenyl-4-sulfonic acid benzoylamide (1356496-11-1)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 0.0166667h; chemoselective reaction; Inert atmosphere;

DOI:10.1039/c1cc14724b

upstream raw materials:

4-bromo-benzenesulfonic acid amide

4-trifluoromethylphenylboronic acid

Downstream raw materials:

4'-trifluoromethyl-biphenyl-4-sulfonic acid benzoylamide

Refernces