C₅₅H₈₂O₁₈

Base Information

• Chemical Name: C₅₅H₈₂O₁₈
• CAS No.: 289631-29-4
• Molecular Formula: C₅₅H₈₂O₁₈
• Molecular Weight: 1031.25
• Mol file: 289631-29-4.mol

Synonyms:

Chemical Property of C₅₅H₈₂O₁₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₅H₈₂O₁₈

There total 7 articles about C₅₅H₈₂O₁₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C61H96O18Si (289631-40-9) → C55H82O18 (289631-29-4)

Guidance literature:

With tetrabutyl ammonium fluoride; acetic acid; In tetrahydrofuran; at 20 ℃; for 48h;

DOI:10.1248/cpb.48.855

Reference yield:

(3S,4E,6R,7S,8S,9R,10S,11S)-12-triethylsilyloxy-8,10-<(S)-3,4-dimethoxybenzylidenedioxy>-6,11-bis(methoxymethoxy)-3,5,7,9-tetramethyl-4-dodecen-2-one (226079-49-8) → C55H82O18 (289631-29-4)

Guidance literature:

Multi-step reaction with 6 steps

1: 26 percent / LHMDS / tetrahydrofuran / 6.5 h / -78 - -40 °C

2: 80 percent / DDQ / CH₂Cl₂ / 0.67 h / -10 °C

3: 98 percent / AcOH / tetrahydrofuran; H₂O / 2 h / 20 °C

4: Dess-Martin reagent; pyridine / CH₂Cl₂ / 9.5 h / 20 °C

5: NaClO₂; NaH₂PO₄; 2-methyl-2-butene / H₂O; 2-methyl-propan-2-ol / 1 h / 20 °C

6: 0.0085 g / AcOH; TBAF / tetrahydrofuran / 48 h / 20 °C

With pyridine; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; tetrabutyl ammonium fluoride; Dess-Martin periodane; acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane; water; tert-butyl alcohol; 1: Addition / 2: Oxidation / 3: Hydrolysis / 4: Oxidation / 5: Oxidation / 6: Hydrolysis;

DOI:10.1248/cpb.48.855

Reference yield:

(2S,3S,4S,5S,6E,8S,9Z)-4-(tert-butyldimethylsilyloxymethyl)-3-(3,4-dimethoxybenzyloxy)-5-methoxymethoxy-2,6,8-trimethyl-6,9-undecadienal (252006-20-5) → C55H82O18 (289631-29-4)

Guidance literature:

Multi-step reaction with 6 steps

1: 26 percent / LHMDS / tetrahydrofuran / 6.5 h / -78 - -40 °C

2: 80 percent / DDQ / CH₂Cl₂ / 0.67 h / -10 °C

3: 98 percent / AcOH / tetrahydrofuran; H₂O / 2 h / 20 °C

4: Dess-Martin reagent; pyridine / CH₂Cl₂ / 9.5 h / 20 °C

5: NaClO₂; NaH₂PO₄; 2-methyl-2-butene / H₂O; 2-methyl-propan-2-ol / 1 h / 20 °C

6: 0.0085 g / AcOH; TBAF / tetrahydrofuran / 48 h / 20 °C

With pyridine; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; tetrabutyl ammonium fluoride; Dess-Martin periodane; acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane; water; tert-butyl alcohol; 1: Addition / 2: Oxidation / 3: Hydrolysis / 4: Oxidation / 5: Oxidation / 6: Hydrolysis;

DOI:10.1248/cpb.48.855

upstream raw materials:

C₆₁H₉₆O₁₈Si

(3S,4E,6R,7S,8S,9R,10S,11S)-12-triethylsilyloxy-8,10-<(S)-3,4-dimethoxybenzylidenedioxy>-6,11-bis(methoxymethoxy)-3,5,7,9-tetramethyl-4-dodecen-2-one

(2S,3S,4S,5S,6E,8S,9Z)-4-(tert-butyldimethylsilyloxymethyl)-3-(3,4-dimethoxybenzyloxy)-5-methoxymethoxy-2,6,8-trimethyl-6,9-undecadienal

C₆₁H₉₆O₁₇Si