N-(4-nitrobenzyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Base Information

Chemical Name:N-(4-nitrobenzyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
CAS No.:380152-00-1
Molecular Formula:C₁₉H₂₃BN₂O₄
Molecular Weight:354.214
Hs Code.:
DSSTox Substance ID:DTXSID801130084
Nikkaji Number:J1.584.590B

Synonyms:380152-00-1;N-(4-nitrobenzyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline;N-[(4-nitrophenyl)methyl]-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline;4-Nitro-N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]benzenemethanamine;DTXSID801130084;AKOS037647228;AS-72896;CID 11727937;D94068;Benzenemethanamine, 4-nitro-n-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-

Suppliers and Price of N-(4-nitrobenzyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of N-(4-nitrobenzyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:354.1750874
Heavy Atom Count:26
Complexity:484

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CC(=CC=C2)NCC3=CC=C(C=C3)[N+](=O)[O-]

Technology Process of N-(4-nitrobenzyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

There total 6 articles about N-(4-nitrobenzyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: NO₂C₆H₄CHNC₆H₄B(O₂C(CH₃)2C(CH₃)2)

: 274-07-7
benzo[1,3,2]dioxaborole

: 380152-00-1
(4-nitro-benzyl)-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-amine

Guidance literature:: With H₂O; In toluene; slight excess of catecholborane in toluene added dropwise to a stirred soln. of imine in toluene under N2; mixt. stored at room temp. for 24 h; water then added; extn.; flash chromy, Al2O3; elem. anal.;
DOI:10.1139/v01-090

Reference yield:

: 555-16-8
4-nitrobenzaldehdye

: 380152-00-1
(4-nitro-benzyl)-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / activated molecular sieves 4 Angstroem / CH₂Cl₂

2: sodium borohydride / methanol

With sodium tetrahydroborate; 4 A molecular sieve; In methanol; dichloromethane;
DOI:10.1139/v01-090

Reference yield:

: 210907-84-9
3-aminophenylboronic acid pinacolate

: 380152-00-1
(4-nitro-benzyl)-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / activated molecular sieves 4 Angstroem / CH₂Cl₂

2: sodium borohydride / methanol

With sodium tetrahydroborate; 4 A molecular sieve; In methanol; dichloromethane;
DOI:10.1139/v01-090