1-(4-Benzoylphenyl)-2-methylpiperidin

Base Information

• Chemical Name: 1-(4-Benzoylphenyl)-2-methylpiperidin
• CAS No.: 223541-09-1
• Molecular Formula: C₁₉H₂₁NO
• Molecular Weight: 279.382
• Mol file: 223541-09-1.mol

Synonyms:

Chemical Property of 1-(4-Benzoylphenyl)-2-methylpiperidin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-Benzoylphenyl)-2-methylpiperidin

There total 1 articles about 1-(4-Benzoylphenyl)-2-methylpiperidin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-fluorobenzophenone (345-83-5) + 2-Methylpiperidin (109-05-7,3000-79-1) → 1-(4-Benzoylphenyl)-2-methylpiperidin (223541-09-1)

Guidance literature:

for 24h;

DOI:10.1515/znb-1999-0210

Reference yield: 35.0%

1-(4-Benzoylphenyl)-2-methylpiperidin (223541-09-1) → 4-(5-Oxohexylamino)benzophenon (223541-18-2)

Guidance literature:

With Hg(II)-EDTA; water; In ethanol; for 4h;

DOI:10.1515/znb-1999-0210

Reference yield:

1-(4-Benzoylphenyl)-2-methylpiperidin (223541-09-1) → 1-(4-Benzoylphenyl)-2-methyl-3,4,5,6-tetrahydropyridinium-perchlorat

Guidance literature:

Multi-step reaction with 2 steps

1: 35 percent / Hg(II)-EDTA; H₂O / ethanol / 4 h

2: HClO₄ / aq. ethanol

With perchloric acid; Hg(II)-EDTA; water; In ethanol; 1: Oxidation / 2: Cyclization;

DOI:10.1515/znb-1999-0210

upstream raw materials:

4-fluorobenzophenone

2-Methylpiperidin

Downstream raw materials:

4-(5-Oxohexylamino)benzophenon