bis(2,2-diphenyl-2-hydroxyethyl)dimethylammonium bromide

Base Information

• Chemical Name: bis(2,2-diphenyl-2-hydroxyethyl)dimethylammonium bromide
• CAS No.: 2118-04-9
• Molecular Formula: Br*C₃₀H₃₂NO₂
• Molecular Weight: 518.494
• Mol file: 2118-04-9.mol

Synonyms:

Chemical Property of bis(2,2-diphenyl-2-hydroxyethyl)dimethylammonium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis(2,2-diphenyl-2-hydroxyethyl)dimethylammonium bromide

There total 3 articles about bis(2,2-diphenyl-2-hydroxyethyl)dimethylammonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tetramethylammonium bromide (64-20-0) → bis(2,2-diphenyl-2-hydroxyethyl)dimethylammonium bromide (2118-04-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 1eq. n-BuLi / diethyl ether; hexane / 48 h / 20 °C

2: 1eq. n-BuLi / diethyl ether; hexane / 120 h / 20 °C

3: 48 h / 20 °C

With n-butyllithium; In diethyl ether; hexane; 1: deprotonation / 2: deprotonation / 3: Addition;

DOI:10.1016/S0022-328X(99)00473-8

Reference yield:

benzophenone (119-61-9) + lithium dimethylammonium dimethylide → bis(2,2-diphenyl-2-hydroxyethyl)dimethylammonium bromide (2118-04-9)

Guidance literature:

at 20 ℃; for 48h;

DOI:10.1016/S0022-328X(99)00473-8

Reference yield:

tetramethylammonium bromide (64-20-0) + phenyllithium (591-51-5) → bis(2,2-diphenyl-2-hydroxyethyl)dimethylammonium bromide (2118-04-9)

Guidance literature:

With diethyl ether; Behandeln der Reaktionsloesung mit Benzophenon in Aether und Verreiben des erhaltenen Niederschlags mit wss. Bromwasserstoffsaeure und Aether;

upstream raw materials:

benzophenone

tetramethylammonium bromide

phenyllithium

Refernces