2-[(Butan-2-yl)amino]-1-(4-hydroxyphenyl)ethan-1-one

Base Information

• Chemical Name: 2-[(Butan-2-yl)amino]-1-(4-hydroxyphenyl)ethan-1-one
• CAS No.: 860675-39-4
• Molecular Formula: C₁₂H₁₇NO₂
• Molecular Weight: 207.272
• DSSTox Substance ID: DTXSID20697072
• Mol file: 860675-39-4.mol

Synonyms:860675-39-4;DTXSID20697072;2-[(Butan-2-yl)amino]-1-(4-hydroxyphenyl)ethan-1-one

Chemical Property of 2-[(Butan-2-yl)amino]-1-(4-hydroxyphenyl)ethan-1-one

Chemical Property:

• XLogP3: 2.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 207.125928785
• Heavy Atom Count: 15
• Complexity: 198

Purity/Quality:

99%,98%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCC(C)NCC(=O)C1=CC=C(C=C1)O

Technology Process of 2-[(Butan-2-yl)amino]-1-(4-hydroxyphenyl)ethan-1-one

There total 1 articles about 2-[(Butan-2-yl)amino]-1-(4-hydroxyphenyl)ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

SEC-BUTYLAMINE (33966-50-6) + 4'-benzoyloxy-2-bromoacetophenone (5324-15-2) → 2-sec-butylamino-1-(4-hydroxy-phenyl)-ethanone (860675-39-4)

Guidance literature:

With isopropyl alcohol; Erhitzen des Reaktionsprodukts mit wss. Salzsaeure;

DOI:10.1021/ja01227a004

Reference yield:

2-sec-butylamino-1-(4-hydroxy-phenyl)-ethanone (860675-39-4) → 4-(2-(sec-butylamino)-1-hydroxyethyl)phenol

Guidance literature:

With palladium on activated charcoal; water; optically inactive 2-sec-butylamino-1-<4-hydroxy-phenyl>-ethanol-(1) of mp: 162 degree; Hydrogenation;

DOI:10.1021/ja01227a004

Reference yield:

2-sec-butylamino-1-(4-hydroxy-phenyl)-ethanone (860675-39-4) → 4-(2-(sec-butylamino)-1-hydroxyethyl)phenol

Guidance literature:

With palladium on activated charcoal; water; optically inactive 2-sec-butylamino-1-<4-hydroxy-phenyl>-ethanol-(1) of mp: 133 degree; Hydrogenation;

DOI:10.1021/ja01227a004

upstream raw materials:

SEC-BUTYLAMINE

4'-benzoyloxy-2-bromoacetophenone