5324-15-2

Basic information

• Product Name: 4-(bromoacetyl)phenyl benzoate
• Synonyms: 4-(Bromoacetyl)phenyl benzoate; ethanone, 1-[4-(benzoyloxy)phenyl]-2-bromo-
• CAS NO: 5324-15-2
• Molecular Formula: C₁₅H₁₁BrO₃
• Molecular Weight: 319.15
• Mol File: 5324-15-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 433.5°C at 760 mmHg
• Flash Point: 216°C
• Density: 1.466g/cm³
• Vapor Pressure: 1.02E-07mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: 4-(bromoacetyl)phenyl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(bromoacetyl)phenyl benzoate(5324-15-2)
• EPA Substance Registry System: 4-(bromoacetyl)phenyl benzoate(5324-15-2)

Safety Data

• Hazardous Substances Data: 5324-15-2(Hazardous Substances Data)

Usage

General Description

4-(bromoacetyl)phenyl benzoate is a chemical compound with the molecular formula C15H11BrO3. It is the ester of 4-(bromoacetyl)phenol and benzoic acid. 4-(bromoacetyl)phenyl benzoate is often used as a solvent or intermediate in organic synthesis. It has the potential to be used in pharmaceutical and agrochemical applications due to its structural composition. 4-(bromoacetyl)phenyl benzoate is a white to off-white powder that is sparingly soluble in water but soluble in organic solvents. It should be handled with care and stored in a cool, dry place away from heat and flame.

Upstream product

• 2491-38-5 2-bromo-1-(4'-hydroxyphenyl)-1-ethanone 
• 65-85-0 benzoic acid 
• 98-88-4 benzoyl chloride 
• 99-93-4 4-Hydroxyacetophenone 
• 1523-18-8 4-benzoyloxyacetophenone 

Downstream Products

• 99075-26-0 2-ethylamino-1-(4-hydroxy-phenyl)-ethanone 
• 99985-57-6 1-(4-hydroxy-phenyl)-2-isopropylamino-ethanone 
• 87154-81-2 2-(diethylamino)-1-(4-hydroxyphenyl)ethanone 
• 18986-11-3 2-butylamino-1-(4-hydroxy-phenyl)-ethanone 
• 21213-89-8 1-(4-hydroxy-phenyl)-2-methylamino-ethanone 
• 127502-90-3 1-(4-benzoyloxyphenyl)-2-(2-methoxyphenoxy)-1-ethanone 
• 1417611-04-1 4-(1-acetoxy-2-azidoethyl)phenyl benzoate 
• 1417610-93-5 C₁₅H₁₃N₃O₃ 
• 1417611-09-6 C₁₇H₁₅N₃O₄ 
• 1417610-96-8 (R)-4-(2-azido-1-hydroxyethyl)phenyl benzoate 

Relevant articles and documents

Cascade Functionalization of C(sp3)-Br/C(sp2)-H Bonds: Access to Fused Benzo[ e]isoindole-1,3,5-trione via Visible-Light-Induced Reductive Radical Relay Strategy

A reductive radical relay strategy for the construction of fused benzo[e]isoindole-1,3,5-trione through a reaction of α-bromo ketones with maleimides in the presence of Ir(ppy)3 under visible-light irradiation is described. The protocol employs very mild reaction conditions and offers satisfactory yields. Moreover, the reaction proceeds through a cascade C(sp3)-Br/C(sp2)-H functionalization, double C-C bond formation, and oxidative aromatization sequence.

Stereoselective synthesis of cis-2,6-disubstituted morpholines and 1,4-oxathianes by intramolecular reductive etherification of 1,5-diketones

A simple and efficient, Lewis acid catalysed reductive etherification strategy for the stereoselective synthesis of cis-2,6- disubstituted morpholines and 1,4-oxathianes starting from readily available 1,5-diketones has been developed. The strategy is used in the total synthesis of morpholine-based natural products (±)-chelonin A and formal total synthesis of (±)-chelonin C.