5324-15-2

Basic information

• Product Name: 4-(bromoacetyl)phenyl benzoate
• Synonyms: 4-(Bromoacetyl)phenyl benzoate; ethanone, 1-[4-(benzoyloxy)phenyl]-2-bromo-
• CAS NO: 5324-15-2
• Molecular Formula: C₁₅H₁₁BrO₃
• Molecular Weight: 319.15
• Mol File: 5324-15-2.mol

Chemical Properties

• Boiling Point: 433.5°C at 760 mmHg
• Flash Point: 216°C
• Density: 1.466g/cm³
• Vapor Pressure: 1.02E-07mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: 4-(bromoacetyl)phenyl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(bromoacetyl)phenyl benzoate(5324-15-2)
• EPA Substance Registry System: 4-(bromoacetyl)phenyl benzoate(5324-15-2)

Safety Data

• Hazardous Substances Data: 5324-15-2(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
4-(bromoacetyl)phenyl benzoate is utilized as a solvent or intermediate in organic synthesis processes, facilitating the creation of various complex organic compounds.
Used in Pharmaceutical Applications:
Due to its structural properties, 4-(bromoacetyl)phenyl benzoate is considered for use in the pharmaceutical industry, potentially contributing to the development of new drugs or drug formulations.
Used in Agrochemical Applications:
4-(bromoacetyl)phenyl benzoate's potential extends to agrochemicals, where it may be employed in the development of pesticides or other agricultural chemicals to improve crop protection and yield.
It is important to handle 4-(bromoacetyl)phenyl benzoate with care, storing it in a cool, dry place away from heat and flame to ensure safety and maintain its properties.

Upstream product

• 1523-18-8 4-benzoyloxyacetophenone 
• 99-93-4 4-Hydroxyacetophenone 
• 98-88-4 benzoyl chloride 
• 2491-38-5 2-bromo-1-(4'-hydroxyphenyl)-1-ethanone 
• 65-85-0 benzoic acid 

Downstream Products

• 860675-39-4 2-sec-butylamino-1-(4-hydroxy-phenyl)-ethanone 
• 99075-26-0 2-ethylamino-1-(4-hydroxy-phenyl)-ethanone 
• 189506-44-3 2-dimethylamino-1-(4-hydroxy-phenyl)-ethanone 
• 60853-18-1 2-tert-butylamino-1-(4-hydroxy-phenyl)-ethanone 
• 87154-81-2 2-(diethylamino)-1-(4-hydroxyphenyl)ethanone 
• 18986-11-3 2-butylamino-1-(4-hydroxy-phenyl)-ethanone 
• 42146-11-2 2-(benzyl(methyl)amino)-1-(4-hydroxyphenyl)ethan-1-one 
• 21213-89-8 1-(4-hydroxy-phenyl)-2-methylamino-ethanone 
• 500880-98-8 2-amino-1-(4-benzoyloxy-phenyl)-ethanone 

Relevant articles and documents

Cascade Functionalization of C(sp3)-Br/C(sp2)-H Bonds: Access to Fused Benzo[ e]isoindole-1,3,5-trione via Visible-Light-Induced Reductive Radical Relay Strategy

A reductive radical relay strategy for the construction of fused benzo[e]isoindole-1,3,5-trione through a reaction of α-bromo ketones with maleimides in the presence of Ir(ppy)3 under visible-light irradiation is described. The protocol employs very mild reaction conditions and offers satisfactory yields. Moreover, the reaction proceeds through a cascade C(sp3)-Br/C(sp2)-H functionalization, double C-C bond formation, and oxidative aromatization sequence.

Design, synthesis and anti-HIV evaluation of 5-alkyl- 6-(benzo[d][1,3]dioxol-5-alkyl)-2-mercaptopyrimidin-4(3H)-ones as potent HIV-1 NNRTIs

In order to discover and develop the new HIV-1 NNRTIs, a series of 5-alkyl-6-(benzo[d][1,3]dioxol-5-ylalkyl)-2-mercaptopyrimidin-4(3H)-ones was synthesized and screened for their in vitro cytotoxicity against HIV-1. Most of the compounds we synthetized sh

Stereoselective synthesis of cis-2,6-disubstituted morpholines and 1,4-oxathianes by intramolecular reductive etherification of 1,5-diketones

A simple and efficient, Lewis acid catalysed reductive etherification strategy for the stereoselective synthesis of cis-2,6- disubstituted morpholines and 1,4-oxathianes starting from readily available 1,5-diketones has been developed. The strategy is used in the total synthesis of morpholine-based natural products (±)-chelonin A and formal total synthesis of (±)-chelonin C.

USE OF NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID, AND PROCESS FOR PRODUCTION OF THE SAME

The invention provides a reagent for detecting amyloid in a biological tissue which can detect amyloid in vitro and in vivo with high sensitivity using a compound which has affinity with amyloid and is suppressed in toxicity such as mutagenicity. The reagent for detecting amyloid deposited in a biological tissue comprises the compound represented by the following formula (1) or a salt thereof: wherein A1, A2, A3 and A4 independently represent a carbon or a nitrogen, and R3 is a group represented by the following formula: wherein R1 is a radioactive halogen substituent; m is an integer of 0 to 4; and n is an integer of 0 or 1, provided that at least one of A1, A3, A3 and A4 represents a carbon, and R5 binds to a carbon represented by A1, A2, A3 or A4.