bis(tetrahydro-2H-pyran-2-yl) 4,7,10,13-tetrakis(p-tolylsulfonyl)-4,7,10,13-tetraazahexadecane-1,16-diyl ether

Base Information

• Chemical Name: bis(tetrahydro-2H-pyran-2-yl) 4,7,10,13-tetrakis(p-tolylsulfonyl)-4,7,10,13-tetraazahexadecane-1,16-diyl ether
• CAS No.: 167861-79-2
• Molecular Formula: C₅₀H₇₀N₄O₁₂S₄
• Molecular Weight: 1047.39
• Mol file: 167861-79-2.mol

Synonyms:

Chemical Property of bis(tetrahydro-2H-pyran-2-yl) 4,7,10,13-tetrakis(p-tolylsulfonyl)-4,7,10,13-tetraazahexadecane-1,16-diyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis(tetrahydro-2H-pyran-2-yl) 4,7,10,13-tetrakis(p-tolylsulfonyl)-4,7,10,13-tetraazahexadecane-1,16-diyl ether

There total 2 articles about bis(tetrahydro-2H-pyran-2-yl) 4,7,10,13-tetrakis(p-tolylsulfonyl)-4,7,10,13-tetraazahexadecane-1,16-diyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

3-(tetrahydro-2H-pyran-2-yloxy)propyl bromide (33821-94-2) + disodium 1,4,7,10-tetrakis(p-tolylsulfonyl)-1,4,7,10-tetraazadecane-N,N'''-diide (56187-06-5,99892-33-8) → bis(tetrahydro-2H-pyran-2-yl) 4,7,10,13-tetrakis(p-tolylsulfonyl)-4,7,10,13-tetraazahexadecane-1,16-diyl ether (167861-79-2)

Guidance literature:

In N,N-dimethyl-formamide; at 100 ℃; for 1h;

DOI:10.1002/cber.19971300221

Reference yield:

3,4-dihydro-2H-pyran (110-87-2) → bis(tetrahydro-2H-pyran-2-yl) 4,7,10,13-tetrakis(p-tolylsulfonyl)-4,7,10,13-tetraazahexadecane-1,16-diyl ether (167861-79-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / Amberlyst H 15 / - 15 deg C to r.t.

2: 60 percent / dimethylformamide / 1 h / 100 °C

With Amberlyst H 15; In N,N-dimethyl-formamide;

DOI:10.1002/cber.19971300221

Reference yield: 72.0%

bis(tetrahydro-2H-pyran-2-yl) 4,7,10,13-tetrakis(p-tolylsulfonyl)-4,7,10,13-tetraazahexadecane-1,16-diyl ether (167861-79-2) → 4,7,10,13-tetrakis(p-tolylsulfonyl)-4,7,10,13-tetraazahexadecane-1,16-diol

Guidance literature:

With Amberlyst H 15; In methanol; Heating;

DOI:10.1002/cber.19971300221

upstream raw materials:

3-(tetrahydro-2H-pyran-2-yloxy)propyl bromide

disodium 1,4,7,10-tetrakis(p-tolylsulfonyl)-1,4,7,10-tetraazadecane-N,N'''-diide

3,4-dihydro-2H-pyran