N-(4-methoxy-2-methyl-6-nitrophenyl)acetamide

Base Information

• Chemical Name: N-(4-methoxy-2-methyl-6-nitrophenyl)acetamide
• CAS No.: 500562-84-5
• Molecular Formula: C₁₀H₁₂N₂O₄
• Molecular Weight: 224.216
• NSC Number: 128824
• DSSTox Substance ID: DTXSID401250321
• Mol file: 500562-84-5.mol

Synonyms:N-(4-methoxy-2-methyl-6-nitrophenyl)acetamide;500562-84-5;Acetic Acid-(4-Methoxy-2-Methyl-6-Nitro-Anilide);NSC128824;DTXSID401250321;AMY10181;MFCD28975071;NSC-128824;SB79581;s10852;DS-19202;CS-0061291

Chemical Property of N-(4-methoxy-2-methyl-6-nitrophenyl)acetamide

Chemical Property:

• Melting Point: 187 °C
• Boiling Point: 425.7±45.0 °C(Predicted)
• PKA: 13.25±0.70(Predicted)
• Density: 1.283±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 224.07970687
• Heavy Atom Count: 16
• Complexity: 277

Purity/Quality:

99%min. ^*data from raw suppliers

N-(4-Methoxy-2-methyl-6-nitrophenyl)acetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC(=CC(=C1NC(=O)C)[N+](=O)[O-])OC

Technology Process of N-(4-methoxy-2-methyl-6-nitrophenyl)acetamide

There total 1 articles about N-(4-methoxy-2-methyl-6-nitrophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(4-methoxy-2-methylphenyl)acetamide (31601-41-9) → acetic acid-(4-methoxy-2-methyl-6-nitro-anilide) (500562-84-5) + N-(4-methoxy-2-methyl-5-nitrophenyl)acetamide (196194-97-5)

Guidance literature:

With chloroform; water; nitric acid; at -5 ℃;

DOI:10.1039/jr9520004019

Reference yield:

acetic acid-(4-methoxy-2-methyl-6-nitro-anilide) (500562-84-5) → 4-methoxy-2-methyl-6-nitro-aniline (684237-54-5)

Guidance literature:

With hydrogenchloride; methanol;

DOI:10.1039/jr9520004019

Reference yield:

acetic acid-(4-methoxy-2-methyl-6-nitro-anilide) (500562-84-5) → 2-acetamido-5-methoxy-3-nitrobenzoic acid (684237-55-6)

Guidance literature:

With potassium permanganate; water; magnesium sulfate;

DOI:10.1039/jr9520004019

upstream raw materials:

N-(4-methoxy-2-methylphenyl)acetamide

Downstream raw materials:

4-methoxy-2-methyl-6-nitro-aniline

2-acetamido-5-methoxy-3-nitrobenzoic acid

2-amino-5-methoxy-3-nitrobenzoic acid