2,2-Dimethyl-propionic acid (1S,4R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-(5-hydroxy-pentyl)-4-(4-methoxy-benzyloxy)-cyclopent-2-enylmethyl ester

Base Information

Chemical Name:2,2-Dimethyl-propionic acid (1S,4R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-(5-hydroxy-pentyl)-4-(4-methoxy-benzyloxy)-cyclopent-2-enylmethyl ester
CAS No.:896110-62-6
Molecular Formula:C₃₁H₅₂O₆Si
Molecular Weight:548.836
Hs Code.:

2,2-Dimethyl-propionic acid (1S,4R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-(5-hydroxy-pentyl)-4-(4-methoxy-benzyloxy)-cyclopent-2-enylmethyl ester

Synonyms:

Suppliers and Price of 2,2-Dimethyl-propionic acid (1S,4R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-(5-hydroxy-pentyl)-4-(4-methoxy-benzyloxy)-cyclopent-2-enylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,2-Dimethyl-propionic acid (1S,4R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-(5-hydroxy-pentyl)-4-(4-methoxy-benzyloxy)-cyclopent-2-enylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,2-Dimethyl-propionic acid (1S,4R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-(5-hydroxy-pentyl)-4-(4-methoxy-benzyloxy)-cyclopent-2-enylmethyl ester

There total 8 articles about 2,2-Dimethyl-propionic acid (1S,4R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-(5-hydroxy-pentyl)-4-(4-methoxy-benzyloxy)-cyclopent-2-enylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 896110-34-2
benzoic acid 5-[(3'S,5'R)-2'-(tert-butyldimethylsilanyloxymethyl)-3'-(2'',2''-dimethylpropionyloxymethyl)-5'-(4''-methoxybenzyloxy)cyclopent-1'-enyl]pentyl ester

: 896110-62-6
2,2-Dimethyl-propionic acid (1S,4R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-(5-hydroxy-pentyl)-4-(4-methoxy-benzyloxy)-cyclopent-2-enylmethyl ester

Guidance literature:: With potassium carbonate; In methanol; at 20 ℃;
DOI:10.1016/j.tet.2005.11.096

Reference yield:

: 896110-29-5
benzoic acid 5-[(R)-4'-(2'',2''-dimethylpropionyloxymethyl)-6'-oxocyclohex-1'-enyl]pentyl ester

: 896110-62-6
2,2-Dimethyl-propionic acid (1S,4R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-(5-hydroxy-pentyl)-4-(4-methoxy-benzyloxy)-cyclopent-2-enylmethyl ester

Guidance literature:: Multi-step reaction with 7 steps

1.1: CeCl₃*7H₂O; NaBH₄ / methanol / 1 h / 0 °C

2.1: TfOH / diethyl ether / 0 - 20 °C

3.1: ozone / CH₂Cl₂; methanol / -78 °C

3.2: PPh₃ / CH₂Cl₂; methanol / -78 - 20 °C

4.1: piperidine; acetic acid / diethyl ether / 20 h / Heating

5.1: NaBH₄ / methanol / 0.33 h / 0 °C

6.1: imidazole / CH₂Cl₂ / 1 h / 20 °C

7.1: K₂CO₃ / methanol / 20 °C

With piperidine; 1H-imidazole; sodium tetrahydroborate; cerium(III) chloride; trifluorormethanesulfonic acid; potassium carbonate; ozone; acetic acid; In methanol; diethyl ether; dichloromethane; 1.1: Luche reaction;
DOI:10.1016/j.tet.2005.11.096

Reference yield:

: Benzoic acid 5-[(R)-4-(2,2-dimethyl-propionyloxymethyl)-6-hydroxy-cyclohex-1-enyl]-pentyl ester

: 896110-62-6
2,2-Dimethyl-propionic acid (1S,4R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-(5-hydroxy-pentyl)-4-(4-methoxy-benzyloxy)-cyclopent-2-enylmethyl ester

Guidance literature:: Multi-step reaction with 6 steps

1.1: TfOH / diethyl ether / 0 - 20 °C

2.1: ozone / CH₂Cl₂; methanol / -78 °C

2.2: PPh₃ / CH₂Cl₂; methanol / -78 - 20 °C

3.1: piperidine; acetic acid / diethyl ether / 20 h / Heating

4.1: NaBH₄ / methanol / 0.33 h / 0 °C

5.1: imidazole / CH₂Cl₂ / 1 h / 20 °C

6.1: K₂CO₃ / methanol / 20 °C

With piperidine; 1H-imidazole; sodium tetrahydroborate; trifluorormethanesulfonic acid; potassium carbonate; ozone; acetic acid; In methanol; diethyl ether; dichloromethane;
DOI:10.1016/j.tet.2005.11.096