C₄₅H₄₉Cl₂N₅O₁₉P₂

Base Information

Chemical Name:C₄₅H₄₉Cl₂N₅O₁₉P₂
CAS No.:88121-50-0
Molecular Formula:C₄₅H₄₉Cl₂N₅O₁₉P₂
Molecular Weight:1096.76
Hs Code.:

C<sub>45</sub>H<sub>49</sub>Cl<sub>2</sub>N<sub>5</sub>O<sub>19</sub>P<sub>2</sub>

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₄₅H₄₉Cl₂N₅O₁₉P₂

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Technology Process of C₄₅H₄₉Cl₂N₅O₁₉P₂

There total 7 articles about C₄₅H₄₉Cl₂N₅O₁₉P₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-[(2R,3R,4R,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-3-(tetrahydro-furan-2-yloxy)-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione

: 88121-50-0
C₄₅H₄₉Cl₂N₅O₁₉P₂

Guidance literature:: Multi-step reaction with 2 steps

1: tetra-n-butylammonium fluoride / tetrahydrofuran / 2 h

2: 2.)mesitylenesulfonyl tetrazolide (MSTe) / 1.) pyridine 2.) pyridine, 30 deg C, 20 min

With mesitylenesulfonyl tetrazolide; tetrabutyl ammonium fluoride; In tetrahydrofuran;

Reference yield:

: 58-96-8
uridine

: 88121-50-0
C₄₅H₄₉Cl₂N₅O₁₉P₂

Guidance literature:: Multi-step reaction with 4 steps

1: 33 percent / imidazole / dimethylformamide / 1.67 h / Ambient temperature

2: p-toluenesulfonic acid / tetrahydrofuran / 4.5 h

3: tetra-n-butylammonium fluoride / tetrahydrofuran / 2 h

4: 2.)mesitylenesulfonyl tetrazolide (MSTe) / 1.) pyridine 2.) pyridine, 30 deg C, 20 min

With 1H-imidazole; mesitylenesulfonyl tetrazolide; tetrabutyl ammonium fluoride; toluene-4-sulfonic acid; In tetrahydrofuran; N,N-dimethyl-formamide;

Reference yield:

: 54925-67-6
3',5'-bis-O-(tert-butyldimethylsilyl)uridine

: 88121-50-0
C₄₅H₄₉Cl₂N₅O₁₉P₂

Guidance literature:: Multi-step reaction with 3 steps

1: p-toluenesulfonic acid / tetrahydrofuran / 4.5 h

2: tetra-n-butylammonium fluoride / tetrahydrofuran / 2 h

3: 2.)mesitylenesulfonyl tetrazolide (MSTe) / 1.) pyridine 2.) pyridine, 30 deg C, 20 min

With mesitylenesulfonyl tetrazolide; tetrabutyl ammonium fluoride; toluene-4-sulfonic acid; In tetrahydrofuran;