2-AMINO-6-CHLORO-4-(CYANOMETHYL)PYRIDINE-3,5-DICARBONITRILE

Base Information

• Chemical Name: 2-AMINO-6-CHLORO-4-(CYANOMETHYL)PYRIDINE-3,5-DICARBONITRILE
• CAS No.: 19858-57-2
• Molecular Formula: C₉H₄ClN₅
• Molecular Weight: 217.617
• Hs Code.: 2933399090
• Mol file: 19858-57-2.mol

Synonyms:NSC 332472

Chemical Property of 2-AMINO-6-CHLORO-4-(CYANOMETHYL)PYRIDINE-3,5-DICARBONITRILE

Chemical Property:

• Vapor Pressure: 2.36E-08mmHg at 25°C
• Melting Point: 257 °C
• Boiling Point: 451.8°Cat760mmHg
• Flash Point: 227.1°C
• PSA: 110.28000
• Density: 1.51g/cm³
• LogP: 1.70784

Purity/Quality:

99% ^*data from raw suppliers

2-AMINO-6-CHLORO-4-(CYANOMETHYL)PYRIDINE-3,5-DICARBONITRILE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-AMINO-6-CHLORO-4-(CYANOMETHYL)PYRIDINE-3,5-DICARBONITRILE

There total 2 articles about 2-AMINO-6-CHLORO-4-(CYANOMETHYL)PYRIDINE-3,5-DICARBONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

C9H4N5(1-)*K(1+) → 2-amino-6-chloro-4-cyanomethyl-3,5-pyridinedicarbonitrile (19858-57-2)

Guidance literature:

With trichlorophosphate; In isopropyl alcohol; at 25 ℃; for 20h;

DOI:10.1016/j.tetlet.2021.153232

Reference yield:

→ 2-amino-6-chloro-4-cyanomethyl-3,5-pyridinedicarbonitrile (19858-57-2)

Guidance literature:

2-Cyanmethyl-1,1,3,3-tetracyan-propen-Na-salz, konz. HCl, Acetonin;

DOI:10.1039/j39680001252

Reference yield: 97.0%

2-amino-6-chloro-4-cyanomethyl-3,5-pyridinedicarbonitrile (19858-57-2) + diethylamine (109-89-7) → 2-amino-4-(cyanomethyl)-6-(diethylamino)-3,5-pyridinedicarbonitrile (380638-39-1)

Guidance literature:

In 1,4-dioxane; for 1h; Heating;

DOI:10.1007/s00706-003-0006-4

Downstream raw materials:

2-amino-4-(cyanomethyl)-6-(diethylamino)-3,5-pyridinedicarbonitrile

Refernces