(E)-2-bromovinylboronic acid N-methyliminodiacetic ester

Base Information

Chemical Name:(E)-2-bromovinylboronic acid N-methyliminodiacetic ester
CAS No.:1105069-27-9
Molecular Formula:C₇H₉BBrNO₄
Molecular Weight:261.868
Hs Code.:

Synonyms:

Suppliers and Price of (E)-2-bromovinylboronic acid N-methyliminodiacetic ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Sigma-Aldrich
cis-2-Bromovinylboronic acid MIDA ester 90%
1g
$ 265.00

Crysdot
8-(2-Bromovinyl)-4-methyl-2,6-dioxohexahydro-[1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborol-4-ium-8-uide 97%
5g
$ 1602.00

Crysdot
8-(2-Bromovinyl)-4-methyl-2,6-dioxohexahydro-[1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborol-4-ium-8-uide 97%
1g
$ 532.00

Total 1 raw suppliers

Chemical Property of (E)-2-bromovinylboronic acid N-methyliminodiacetic ester

Chemical Property:

Melting Point:153-159°C (Decomp.)

Purity/Quality:

98%,99%, ^*data from raw suppliers

cis-2-Bromovinylboronic acid MIDA ester 90% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses The (Z)-(2-Bromovinyl)-MIDA boronate is a unique building block for the incorporation of cis-olefin for small molecule synthesis. Burke and coworkers have displayed the extreme versatility of this building block in the construction of polyene-containing natural product motifs.

Technology Process of (E)-2-bromovinylboronic acid N-methyliminodiacetic ester

There total 2 articles about (E)-2-bromovinylboronic acid N-methyliminodiacetic ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 41309-43-7,70737-20-1,13682-94-5
(2-bromovinyl)trimethylsilane

: 71160-37-7
sodium methyliminodiacetate

: 1105069-27-9,1104636-68-1
(E)-2-bromovinylboronic acid N-methyliminodiacetic ester

Guidance literature:: (2-bromovinyl)trimethylsilane; With boron tribromide; In dichloromethane; at 0 ℃; Inert atmosphere;

sodium methyliminodiacetate; In dichloromethane; acetonitrile; at 0 - 5 ℃; stereoselective reaction; Inert atmosphere;
DOI:10.1016/j.tet.2008.11.010

Reference yield: 60.0%

: 4408-64-4
N-methyliminodiacetic acid

: 114701-85-8
(E)-(2-bromoethenyl)dibromoborane

: 1105069-27-9,1104636-68-1
(E)-2-bromovinylboronic acid N-methyliminodiacetic ester

Guidance literature:: With 2,6-dimethylpyridine; In dimethyl sulfoxide; treatment of boron compd. with acetic acid deriv. in presence of lutidine in DMSO at 0 with warming to 23°C;
DOI:10.1021/ja078129x

Reference yield: 92.0%

: 1105069-27-9,1104636-68-1
(E)-2-bromovinylboronic acid N-methyliminodiacetic ester

: 6783-05-7
trans-2-phenylvinylboronic acid

: 6-methyl-2-((1E,3E)-4-phenylbuta-1,3-dien-1-yl)-1,3,6,2-dioxazaborocane-4,8-dione

Guidance literature:: With potassium fluoride; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; In toluene; at 23 ℃; for 24h;
DOI:10.1021/ja078129x