(E)-2-(2,4-Difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

Chemical Name:(E)-2-(2,4-Difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.:736987-78-3
Molecular Formula:C14H17 B F2 O2
Molecular Weight:266.096
Hs Code.:2934999090
ChEMBL ID:CHEMBL2315713
DSSTox Substance ID:DTXSID70584786
Wikidata:Q82476509
Mol file:736987-78-3.mol

Synonyms:736987-78-3;(E)-2-(2,4-Difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2-[(E)-2-(2,4-Difluorophenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;trans-2-(2,4-Difluorophenyl)vinylboronic acid pinacol ester;E-2-(2,4-DIFLUOROPHENYL)VINYLBORONIC ACID, PINACOL ESTER;E-2-(2 4-DIFLUOROPHENYL)VINYLBORONIC AC&;SCHEMBL692990;SCHEMBL692991;CHEMBL2315713;DTXSID70584786;BMZXZTQQERUFEM-BQYQJAHWSA-N;MFCD08276857;AKOS015999407;BS-22571;CS-0175486;EN300-802064;EN300-7370234;A866050;Z2315585588;trans-2-(2,4-Difluorophenyl)vinylboronic acid pinacol ester, 96%;2-[2-(2,4-DIFLUOROPHENYL)ETHENYL]-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE

Suppliers and Price of (E)-2-(2,4-Difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
E-2-(2,4-Difluorophenyl)vinylboronicacid,pinacolester
50mg
$ 55.00

Sigma-Aldrich
trans-2-(2,4-Difluorophenyl)vinylboronic acid pinacol ester 96%
1g
$ 111.00

Sigma-Aldrich
trans-2-(2,4-Difluorophenyl)vinylboronic acid pinacol ester 96%
5g
$ 407.00

Matrix Scientific
(E)-2-(2,4-Difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 95+%
1g
$ 303.00

Crysdot
(E)-2-(2,4-Difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 95+%
5g
$ 409.00

American Custom Chemicals Corporation
TRANS-2-(2,4-DIFLUOROPHENYL)VINYLBORONIC ACID PINACOL ESTER 95.00%
1G
$ 321.30

Total 14 raw suppliers

Chemical Property of (E)-2-(2,4-Difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

Vapor Pressure:0.0129mmHg at 25°C
Refractive Index:n20/D 1.503
Boiling Point:103-105 °C0.2-0.3 mm Hg
Flash Point:>230 °F
PSA：18.46000
Density:1.099 g/mL at 25 °C
LogP:3.60940
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:266.1289663
Heavy Atom Count:19
Complexity:341

Purity/Quality:

97% ^*data from raw suppliers

E-2-(2,4-Difluorophenyl)vinylboronicacid,pinacolester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C=CC2=C(C=C(C=C2)F)F
Isomeric SMILES:B1(OC(C(O1)(C)C)(C)C)/C=C/C2=C(C=C(C=C2)F)F

Technology Process of (E)-2-(2,4-Difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 2 articles about (E)-2-(2,4-Difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 288101-48-4
2-(2,4-difluorophenyl)-4,4, 5,5-tetramethyl-1,3,2-dioxaborolane

: 1105069-27-9,1104636-68-1
(E)-2-bromovinylboronic acid N-methyliminodiacetic ester

: 736987-78-3
trans-2-(2,4-difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:: With potassium phosphate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; water; In tetrahydrofuran; at 90 ℃; for 24h; chemoselective reaction; Inert atmosphere;
DOI:10.1002/anie.201406714

Reference yield: 76.0%

: 73183-34-3
bis(pinacol)diborane

: 302912-34-1
2,4-difluoroethynylbenzene

: 736987-78-3
trans-2-(2,4-difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:: With tetrabutylammonium tetrafluoroborate; In methanol; at 20 ℃; Electrochemical reaction;
DOI:10.1002/chem.202101132

Reference yield: 52.0%

: 736987-78-3
trans-2-(2,4-difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 1-(4‐(1,2,3‐thiadiazol‐5‐yl)benzyl)‐2,4,6‐triphenylpyridin‐1‐ium tetrafluoroborate

: (E)-5-{4-[3-(2,4-difluorophenyl)allyl]phenyl}-1,2,3-thiadiazole

Guidance literature:: With potassium phosphate; ethanol; 2C₂H₃O₂^(1-)*C₁₂H₈N₂*(x)H₂O*Ni⁽²⁺⁾; In 1,4-dioxane; at 60 ℃; for 24h; Schlenk technique; Sealed tube; Inert atmosphere;
DOI:10.1055/s-0037-1610084