Z-Glut>-OBu^t

Base Information

• Chemical Name: Z-Glut>-OBu^t
• CAS No.: 25456-77-3
• Molecular Formula: C₂₆H₃₈N₂O₉
• Molecular Weight: 522.596
• Mol file: 25456-77-3.mol

Synonyms:

Chemical Property of Z-Glut>-OBu^t

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Z-Glut>-OBu^t

There total 5 articles about Z-Glut>-OBu^t which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(benzyloxycarbonyl)-L-glutamic acid α-t-butyl ester dicyclohexylamine salt (34897-61-5) → Z-Glut>-OBut (25456-77-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 2.) H₂, 3.5 M HCl / 2.) Pd-black / 1.) ether, 20 deg C; 2.) methanol, acetic acid, 5 h, 20 deg C

2: 65.3 percent

3: base

With hydrogenchloride; hydrogen; palladium;

Reference yield:

N-(benzyloxycarbonyl)-γ-L-glutamyl-L-glutamic acid, α,α'-di-tert-butyl γ-methyl triester (23736-78-9) → Z-Glut>-OBut (25456-77-3)

Guidance literature:

With base;

Reference yield:

Z-Glu(OPcp)-OBut (25456-73-9) → Z-Glut>-OBut (25456-77-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 65.3 percent

2: base

With base;

upstream raw materials:

N-(benzyloxycarbonyl)-γ-L-glutamyl-L-glutamic acid, α,α'-di-tert-butyl γ-methyl triester

Z-Glu(OPcp)-OBu^t

N-(benzyloxycarbonyl)-L-glutamic acid α-t-butyl ester dicyclohexylamine salt

α-tert-butyl-γ-methyl L-Glu diester hydrochloride

Downstream raw materials:

Z-Glut>-OBu^t

HCl*Glut>-OBu^t