C₂₄H₂₆ClNO₅

Base Information

• Chemical Name: C₂₄H₂₆ClNO₅
• CAS No.: 1239897-03-0
• Molecular Formula: C₂₄H₂₆ClNO₅
• Molecular Weight: 443.927
• Mol file: 1239897-03-0.mol

Synonyms:

Chemical Property of C₂₄H₂₆ClNO₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₂₆ClNO₅

There total 18 articles about C₂₄H₂₆ClNO₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C24H28ClNO6 (1239897-04-1) → C24H26ClNO5 + C24H26ClNO5 (1239897-03-0)

Guidance literature:

With 4-pyrrolidin-1-ylpyridine; methanesulfonyl chloride; In toluene; at -10 - -5 ℃; for 1.5h; optical yield given as %ee; enantioselective reaction;

DOI:10.1021/jo101638r

Reference yield:

C24H28ClNO6 (1239897-04-1) → 1-(benzyloxymethyl)-4-(2-chloroethyl)-2-(4-methoxybenzyl)-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione (1127249-86-8) + C24H26ClNO5 + C24H26ClNO5 (1239897-03-0)

Guidance literature:

With 4-pyrrolidin-1-ylpyridine; methanesulfonyl chloride; In toluene; at -10 - -5 ℃; for 3.5h; optical yield given as %ee; enantioselective reaction;

DOI:10.1021/jo101638r

Reference yield:

3-(2-chloroethyl)-4-methyleneoxetan-2-one → C24H26ClNO5 + C24H26ClNO5 (1239897-03-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 2-hydroxypyridin / 1,2-dichloro-ethane / 23 - 48 °C / Microwave irradiation; Inert atmosphere

2.1: morpholine; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran / 1.17 h / -5 °C / Inert atmosphere

2.2: pH Ca_. 3 / Inert atmosphere

3.1: 4-pyrrolidin-1-ylpyridine; methanesulfonyl chloride / toluene / 1.5 h / -10 - -5 °C

With morpholine; 2-hydroxypyridin; tetrakis(triphenylphosphine) palladium⁽⁰⁾; 4-pyrrolidin-1-ylpyridine; methanesulfonyl chloride; In tetrahydrofuran; 1,2-dichloro-ethane; toluene;

DOI:10.1021/jo101638r

upstream raw materials:

C₂₇H₃₂ClNO₆

C₂₇H₃₂ClNO₆

C₂₄H₂₈ClNO₆

(R)-O-benzyl-N-PMB serine