Technology Process of C31H37ClN4O5S
There total 5 articles about C31H37ClN4O5S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: bis-triphenylphosphine-palladium(II) chloride; potassium carbonate / 1,2-dimethoxyethane; water / 1 h / 70 °C
2: caesium carbonate / N,N-dimethyl-formamide / 60 °C
3: water; lithium hydroxide / tetrahydrofuran; methanol / 20 °C
4: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / tetrahydrofuran
5: sulfonamide / 1,2-dioxacyclohexane / 100 °C
6: trifluoroacetic acid / dichloromethane
With
bis-triphenylphosphine-palladium(II) chloride; sulfonamide; water; potassium carbonate; caesium carbonate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; lithium hydroxide;
In
tetrahydrofuran; 1,2-dioxacyclohexane; methanol; 1,2-dimethoxyethane; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.04.113
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sulfonamide / 1,2-dioxacyclohexane / 100 °C
2: trifluoroacetic acid / dichloromethane
With
sulfonamide; trifluoroacetic acid;
In
1,2-dioxacyclohexane; dichloromethane;
DOI:10.1016/j.bmcl.2012.04.113
- Guidance literature:
-
Multi-step reaction with 3 steps
1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / tetrahydrofuran
2: sulfonamide / 1,2-dioxacyclohexane / 100 °C
3: trifluoroacetic acid / dichloromethane
With
sulfonamide; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
tetrahydrofuran; 1,2-dioxacyclohexane; dichloromethane;
DOI:10.1016/j.bmcl.2012.04.113