879498-90-5

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
Tert-butyl 2-bromo-3-cyclohexyl-1H-indole-6-carboxylate is used as a building block in the synthesis of various pharmaceutical and agrochemical compounds. Its unique structural features and reactivity make it a valuable intermediate for the development of new drugs and agrochemicals with improved efficacy and selectivity.
Used in Medicinal Chemistry and Drug Development:
Due to its structural features and potential biological activities, tert-butyl 2-bromo-3-cyclohexyl-1H-indole-6-carboxylate is used as a starting material in medicinal chemistry and drug development. Researchers can modify its structure to explore its potential as a therapeutic agent or to improve the properties of existing drugs.
Used in the Development of New Materials and Compounds:
The unique structure of tert-butyl 2-bromo-3-cyclohexyl-1H-indole-6-carboxylate may also make it useful in the development of new materials and compounds. Its reactivity and functional groups can be exploited to create novel materials with specific properties for various applications.

Upstream product

• 494799-76-7 2-bromo-3-cyclohexyl-1H-indole-6-carboxylic acid 
• 507-19-7 t-butyl bromide 
• 494799-19-8 methyl 2-bromo-3-cyclohexyl-1H-indole-6-carboxylate 
• 108-94-1 cyclohexanone 
• 50820-65-0 indole-6-carboxylic acid methyl ester 
• 1670-82-2 Indole-6-carboxylic acid 
• 494799-16-5 3-(cyclohex-1-en-1-yl)-1H-indole-6-carboxylic acid 
• 494799-17-6 3-cyclohexyl-1-methyl-1H-indole-6-carboxylic acid 
• 494799-18-7 methyl 3-cyclohexyl-1H-indole-6-carboxylate 
• 36805-97-7 N,N-dimethylformamide di-tert-butyl acetal 
• 879498-89-2 tert-butyl 3-cyclohexyl-1H-indole-6-carboxylate 

Downstream Products

• 958002-18-1 1H-indole-6-carboxylic acid, 3-cyclohexyl-2-(2-formyl-4-methoxyphenyl)-, 1,1-dimethylethyl ester 
• 958030-50-7 3-cyclohexyl-2-[2-formyl-4-phenylmethoxy-phenyl]-1H-indole-6-carboxylic acid 1,1-dimethylethyl ester 
• 1208130-14-6 tert-butyl 2-bromo-3-cyclohexyl-1-methyl-1H-indole-6-carboxylate 
• 886041-47-0 tert-butyl 2-bromo-3-cyclohexyl-1-(2-methoxy-2-oxoethyl)-1H-indole-6-carboxylate 
• 1045704-98-0 13-cyclohexyl-7H-indolo[2,1-a][2]benzazepine-6,10-dicarboxylic acid 10-(1,1-dimethylethyl) 6-methyl ester 
• 1059700-82-1 (1aR,12bS)-8-cyclohexyl-N-(isopropylsulfonyl)-1,1a,2,12b-tetrahydro-11-methoxy-1a-[(1S,4S)-5-isobutyl-2,5-diazabicyclo[2.2.1]heptane-2-carbonyl]cycloprop[d]indolo[2,1-a][2]benzazepine-5-carboxamide 
• 1059700-84-3 (1aS,12bR)-8-cyclohexyl-N-(isopropylsulfonyl)-1,1a,2,12b-tetrahydro-11-methoxy-1a-[(1S,4S)-5-isobutyl-2,5-diazabicyclo[2.2.1]heptane-2-carbonyl]cycloprop[d]indolo[2,1-a][2]benzazepine-5-carboxamide 

Relevant academic research and scientific papers

Finger-loop inhibitors of the HCV NS5b polymerase. Part 1: Discovery and optimization of novel 1,6- and 2,6-macrocyclic indole series

Novel conformationaly constrained 1,6- and 2,6-macrocyclic HCV NS5b polymerase inhibitors, in which either the nitrogen or the phenyl ring in the C2 position of the central indole core is tethered to an acylsulfamide acid bioisostere, have been designed and tested for their anti-HCV potency. This transformational route toward non-zwitterionic finger loop-directed inhibitors led to the discovery of derivatives with improved cell potency and pharmacokinetic profile.

Cyclopropyl Fused Indolobenzazepine HCV NS5B Inhibitors

The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Compounds for the Treatment of Hepatitis C

The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.

CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV NS5B INHIBITORS

The invention encompasses compounds of formula (I) as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV

Compounds for the Treatment of Hepatitis C

The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.

Compounds for the Treatment of Hepatitis C

The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.

Compounds for the Treatment of Hepatitis C

The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.

Compounds for the Treatment of Hepatitis C

The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.

Compounds for the Treatment of Hepatitis C

The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.

Compounds for the Treatment of Hepatitis C

The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.