2-tert-butyl-4-(2-ethoxyphenyl)-5-aminophenol

Base Information

Chemical Name:2-tert-butyl-4-(2-ethoxyphenyl)-5-aminophenol
CAS No.:873055-73-3
Molecular Formula:C₁₈H₂₃NO₂
Molecular Weight:285.386
Hs Code.:

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Chemical Property of 2-tert-butyl-4-(2-ethoxyphenyl)-5-aminophenol

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Technology Process of 2-tert-butyl-4-(2-ethoxyphenyl)-5-aminophenol

There total 7 articles about 2-tert-butyl-4-(2-ethoxyphenyl)-5-aminophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 873055-72-2
2-tert-butyl-4-(2-ethoxyphenyl)-5-nitrophenol

: 873055-73-3
2-tert-butyl-4-(2-ethoxyphenyl)-5-aminophenol

Guidance literature:: In methanol;

Reference yield:

: 213211-69-9
(2-ethoxyphenyl)boronic acid

: 873055-73-3
2-tert-butyl-4-(2-ethoxyphenyl)-5-aminophenol

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / Pd(PPh₃)4 / water; N,N-dimethyl-formamide

2: methanol

With potassium carbonate; Pd(PPh₃)4; In methanol; water; N,N-dimethyl-formamide;

Reference yield:

: 88-18-6
2-tert-Butylphenol

: 873055-73-3
2-tert-butyl-4-(2-ethoxyphenyl)-5-aminophenol

Guidance literature:: Multi-step reaction with 6 steps

1: N-Bromosuccinimide / acetonitrile / 20 °C

2: triethylamine / dichloromethane / 2 h / 0 °C

3: sulfuric acid; potassium nitrate / 3.5 h / 0 °C

4: potassium hydroxide / methanol / 3 h / 20 °C

5: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide; water / 3 h / 90 °C / Inert atmosphere

6: hydrogen / methanol / 2 h / 20 °C / 760.05 Torr

With N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sulfuric acid; hydrogen; potassium carbonate; potassium nitrate; triethylamine; potassium hydroxide; In methanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;