trans-1,2-Diphenyl-1-keto-2-decen

Base Information

• Chemical Name: trans-1,2-Diphenyl-1-keto-2-decen
• CAS No.: 38821-30-6
• Molecular Formula: C₂₂H₂₆O
• Molecular Weight: 306.448
• Mol file: 38821-30-6.mol

Synonyms:

Chemical Property of trans-1,2-Diphenyl-1-keto-2-decen

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-1,2-Diphenyl-1-keto-2-decen

There total 4 articles about trans-1,2-Diphenyl-1-keto-2-decen which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2,2-trifluoroethyl 1-octanesulfonate + benzil (134-81-6) → trans-1,2-Diphenyl-1-keto-2-decen (38821-30-6) + cis-1,2-Diphenyl-1-keto-2-decen (38821-29-3)

Guidance literature:

2,2,2-trifluoroethyl 1-octanesulfonate; With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere; Schlenk technique;

benzil; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere; Schlenk technique;

In tetrahydrofuran; at 20 - 65 ℃; for 1h; Overall yield = 41 %; Inert atmosphere; Schlenk technique;

DOI:10.1002/ejoc.201701766

Reference yield:

1,2-Diphenyl-2-brom-1-decanon (38821-26-0) → trans-1,2-Diphenyl-1-keto-2-decen (38821-30-6)

Guidance literature:

With 2,3,5-trimethyl-pyridine;

DOI:10.1021/jo00949a025

Reference yield:

1,1-Diphenyl-decanol-(1) (21236-83-9) → trans-1,2-Diphenyl-1-keto-2-decen (38821-30-6)

Guidance literature:

Multi-step reaction with 4 steps

1: Ac₂O / Heating

3: (bromination)

4: collidine

With 2,3,5-trimethyl-pyridine; acetic anhydride;

DOI:10.1021/jo00949a025

upstream raw materials:

1,2-Diphenyl-2-brom-1-decanon

1,1-Diphenyl-decanol-⁽¹⁾

α-octyl deoxybenzoin

benzil

Downstream raw materials:

1,2-Diphenyl-3-ethoxy-1-decen

1,2-Diphenyl-1,3-decadien

trans-1,2-Diphenyl-2-decen-1-ol