(S)-(-)-(2-hydroxy-2-phenyl-1-ethyl)-phenyl thioether

Base Information

• Chemical Name: (S)-(-)-(2-hydroxy-2-phenyl-1-ethyl)-phenyl thioether
• CAS No.: 67210-34-8
• Molecular Formula: C₁₄H₁₄OS
• Molecular Weight: 230.331
• Mol file: 67210-34-8.mol

Synonyms:

Chemical Property of (S)-(-)-(2-hydroxy-2-phenyl-1-ethyl)-phenyl thioether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-(-)-(2-hydroxy-2-phenyl-1-ethyl)-phenyl thioether

There total 79 articles about (S)-(-)-(2-hydroxy-2-phenyl-1-ethyl)-phenyl thioether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-phenyl-2-(phenylthio)ethanone (16222-10-9) → 1-phenyl-2-phenylsulfanyl-ethanol (67210-34-8,67210-39-3,121053-49-4,16162-51-9)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 ℃; for 3h;

DOI:10.1246/bcsj.54.817

Reference yield: 98.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + thiophenol (108-98-5) → 1-phenyl-2-phenylsulfanyl-ethanol (67210-34-8,67210-39-3,121053-49-4,16162-51-9)

Guidance literature:

With iodine; dimethyl sulfoxide; at 60 ℃; Reagent/catalyst; Temperature; regioselective reaction; Catalytic behavior; Green chemistry;

DOI:10.1016/j.tetlet.2017.04.043

Reference yield: 98.0%

sodium thiophenolate (930-69-8) + (S)-1-phenyl-2-(tosyloxy)ethanol (40435-14-1) → (S)-(-)-(2-hydroxy-2-phenyl-1-ethyl)-phenyl thioether (16162-51-9,67210-39-3,121053-49-4,67210-34-8)

Guidance literature:

In tetrahydrofuran; at 20 ℃;

DOI:10.1021/ja052548h

upstream raw materials:

1-phenyl-2-(phenylthio)ethanone

styrene oxide

thiophenol

styrene

Downstream raw materials:

1-bromo-1-phenyl-2-phenylthioethane

benzaldehyde

(2-methoxy-2-phenylethyl)(phenyl)sulfane

erythro-2-(phenylsulfinyl)-1-phenyl-1-ethanol