N-benzyl-5,11,17,23-tetra-tert-butyl-25,27-dihydroxy-26,28-(4'R,8'R-diphenyl-6'-aza-3',9'-dioxaundecane)-dioxycalix[4]arene

Base Information

• Chemical Name: N-benzyl-5,11,17,23-tetra-tert-butyl-25,27-dihydroxy-26,28-(4'R,8'R-diphenyl-6'-aza-3',9'-dioxaundecane)-dioxycalix[4]arene
• CAS No.: 1148038-08-7
• Molecular Formula: C₇₁H₈₅NO₆
• Molecular Weight: 1048.46
• Mol file: 1148038-08-7.mol

Synonyms:

Chemical Property of N-benzyl-5,11,17,23-tetra-tert-butyl-25,27-dihydroxy-26,28-(4'R,8'R-diphenyl-6'-aza-3',9'-dioxaundecane)-dioxycalix[4]arene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-benzyl-5,11,17,23-tetra-tert-butyl-25,27-dihydroxy-26,28-(4'R,8'R-diphenyl-6'-aza-3',9'-dioxaundecane)-dioxycalix[4]arene

There total 1 articles about N-benzyl-5,11,17,23-tetra-tert-butyl-25,27-dihydroxy-26,28-(4'R,8'R-diphenyl-6'-aza-3',9'-dioxaundecane)-dioxycalix[4]arene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

bis N-<(1R)-1-hydroxyphenylethan-2-yl> benzylamine (143668-56-8) + 25,27-bis(2-bromoethoxy)-26,28-dihydroxy-5,11,17,23-tetra(tert-butyl)calixarene (444004-64-2,197228-58-3) → N-benzyl-5,11,17,23-tetra-tert-butyl-25,27-dihydroxy-26,28-(4'R,8'R-diphenyl-6'-aza-3',9'-dioxaundecane)-dioxycalix[4]arene (1148038-08-7)

Guidance literature:

bis N-<(1R)-1-hydroxyphenylethan-2-yl> benzylamine; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 2h; Inert atmosphere;

25,27-bis(2-bromoethoxy)-26,28-dihydroxy-5,11,17,23-tetra(tert-butyl)calixarene; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 48h; Inert atmosphere;

DOI:10.1016/j.tet.2009.01.087

Reference yield:

N-benzyl-5,11,17,23-tetra-tert-butyl-25,27-dihydroxy-26,28-(4'R,8'R-diphenyl-6'-aza-3',9'-dioxaundecane)-dioxycalix[4]arene (1148038-08-7) + D-phenylalanine methyl ester hydrochloride (13033-84-6) → C10H13NO2*C71H85NO6*ClH

Guidance literature:

In chloroform; at 25 ℃; Thermodynamic data; Kinetics;

DOI:10.1016/j.tet.2009.01.087

Reference yield:

N-benzyl-5,11,17,23-tetra-tert-butyl-25,27-dihydroxy-26,28-(4'R,8'R-diphenyl-6'-aza-3',9'-dioxaundecane)-dioxycalix[4]arene (1148038-08-7) + D-alanine methyl ester hydrochloride (14316-06-4) → C4H9NO2*C71H85NO6*ClH

Guidance literature:

In chloroform; at 25 ℃; Thermodynamic data; Kinetics;

DOI:10.1016/j.tet.2009.01.087

upstream raw materials:

bis N-<(1R)-1-hydroxyphenylethan-2-yl> benzylamine

25,27-bis(2-bromoethoxy)-26,28-dihydroxy-5,11,17,23-tetra(tert-butyl)calixarene