dibenzyl [amino(dimethylamino)methylidene]phosphoramidate

Base Information

• Chemical Name: dibenzyl [amino(dimethylamino)methylidene]phosphoramidate
• CAS No.: 50725-09-2
• Molecular Formula: C17H22 N3 O3 P
• Molecular Weight: 347.3486
• Mol file: 50725-09-2.mol

Synonyms:Phosphoramidicacid, [amino(dimethylamino)methylene]-, dibenzyl ester (6CI); DibenzylN,N-dimethyl-N'-phosphoroguanidine; NSC 269958

Chemical Property of dibenzyl [amino(dimethylamino)methylidene]phosphoramidate

Chemical Property:

• Vapor Pressure: 2.45E-09mmHg at 25°C
• Boiling Point: 479°C at 760 mmHg
• Flash Point: 243.5°C
• Density: 1.19g/cm³

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dibenzyl [amino(dimethylamino)methylidene]phosphoramidate

There total 2 articles about dibenzyl [amino(dimethylamino)methylidene]phosphoramidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phosphoric acid dibenzyl ester (1623-08-1) + 1,1-dimethylguanidine dihydrogensulfate (311-77-3,1186-46-5) → N'-(bis-benzyloxy-phosphoryl)-N,N-dimethyl-guanidine (50725-09-2)

Guidance literature:

With sodium hydroxide; In tetrachloromethane;

DOI:10.1021/ja00805a022

Reference yield:

Dibenzyl phosphite (17176-77-1) + N,N-Dimethyl-guanidine (6145-42-2) → N'-(bis-benzyloxy-phosphoryl)-N,N-dimethyl-guanidine (50725-09-2)

Guidance literature:

With tetrachloromethane; sodium hydroxide;

Reference yield:

N'-(bis-benzyloxy-phosphoryl)-N,N-dimethyl-guanidine (50725-09-2) → N,N-dimethyl-N'-phosphoroguanidine monobenzyl ester (50725-11-6)

Guidance literature:

With pyridine hydrochloride; In N,N-dimethyl-formamide; acetone;

DOI:10.1021/ja00805a022

upstream raw materials:

Dibenzyl phosphite

N,N-Dimethyl-guanidine

phosphoric acid dibenzyl ester

1,1-dimethylguanidine dihydrogensulfate

Downstream raw materials:

N,N-dimethyl-N'-phosphoroguanidine monobenzyl ester