6-<methyl>-5-chloro-2,4-diaminoquinazoline

Base Information

Chemical Name:6-<methyl>-5-chloro-2,4-diaminoquinazoline
CAS No.:120296-61-9
Molecular Formula:C₁₈H₁₃ClF₃N₅O₃
Molecular Weight:439.781
Hs Code.:

6-<<p-Carboxy-N-(trifluoroacetyl)anilino>methyl>-5-chloro-2,4-diaminoquinazoline

Synonyms:

Suppliers and Price of 6-<methyl>-5-chloro-2,4-diaminoquinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-<methyl>-5-chloro-2,4-diaminoquinazoline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-<methyl>-5-chloro-2,4-diaminoquinazoline

There total 1 articles about 6-<methyl>-5-chloro-2,4-diaminoquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 407-25-0
trifluoroacetic anhydride

: 57343-54-1
6-<(p-carboxyanilino)methyl>-5-chloro-2,4-diaminoquinazoline

: 120296-61-9
6-<methyl>-5-chloro-2,4-diaminoquinazoline

Guidance literature:: for 7h;
DOI:10.1021/jm00127a026

Reference yield:

: 120296-61-9
6-<methyl>-5-chloro-2,4-diaminoquinazoline

: 120296-51-7
N^α-(4-Amino-4-deoxy-5-chloro-5,8-dideazapteroyl)-L-ornithine

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) Et₃N, i-BuOCOCl / 1.) DMF, 0 deg C, 2.) 0 deg C

2: 28 percent / 10 percent NH₄OH / 1.25 h

3: 49 percent / CF₃COOH / Ambient temperature

With ammonium hydroxide; triethylamine; trifluoroacetic acid; isobutyl chloroformate;
DOI:10.1021/jm00127a026

Reference yield:

: 120296-61-9
6-<methyl>-5-chloro-2,4-diaminoquinazoline

: 120296-65-3
N^α-(4-Amino-4-deoxy-5-chloro-5,8-dideazapteroyl)-N^δ-(tert-butyloxycarbonyl)-L-ornithine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Et₃N, i-BuOCOCl / 1.) DMF, 0 deg C, 2.) 0 deg C

2: 28 percent / 10 percent NH₄OH / 1.25 h

With ammonium hydroxide; triethylamine; isobutyl chloroformate;
DOI:10.1021/jm00127a026