{[2-[4-(2-{[1-Methoxycarbonyl-1-phenyl-meth-(Z)-ylidene]-hydrazono}-1-methyl-propylidene)-[1,3]dithietan-2-ylidene]-1-methyl-prop-(Z)-ylidene]-hydrazono}-phenyl-acetic acid methyl ester

Base Information

• Chemical Name: {[2-[4-(2-{[1-Methoxycarbonyl-1-phenyl-meth-(Z)-ylidene]-hydrazono}-1-methyl-propylidene)-[1,3]dithietan-2-ylidene]-1-methyl-prop-(Z)-ylidene]-hydrazono}-phenyl-acetic acid methyl ester
• CAS No.: 107798-24-3
• Molecular Formula: C₂₈H₂₈N₄O₄S₂
• Molecular Weight: 548.687
• Mol file: 107798-24-3.mol

Synonyms:

Chemical Property of {[2-[4-(2-{[1-Methoxycarbonyl-1-phenyl-meth-(Z)-ylidene]-hydrazono}-1-methyl-propylidene)-[1,3]dithietan-2-ylidene]-1-methyl-prop-(Z)-ylidene]-hydrazono}-phenyl-acetic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {[2-[4-(2-{[1-Methoxycarbonyl-1-phenyl-meth-(Z)-ylidene]-hydrazono}-1-methyl-propylidene)-[1,3]dithietan-2-ylidene]-1-methyl-prop-(Z)-ylidene]-hydrazono}-phenyl-acetic acid methyl ester

There total 6 articles about {[2-[4-(2-{[1-Methoxycarbonyl-1-phenyl-meth-(Z)-ylidene]-hydrazono}-1-methyl-propylidene)-[1,3]dithietan-2-ylidene]-1-methyl-prop-(Z)-ylidene]-hydrazono}-phenyl-acetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 9.0%

carbon disulfide (75-15-0,12122-00-8) + triphenyl<1-methyl-2-((phenyl(methoxycarbonyl)methylene)hydrazono)propylidene>phosphorane (107769-77-7) → 2,3-dimethyl-9-phenyl-9H-pyrazolo<5,1-b><1,3>benzothiazine (107769-86-8) + {[2-[4-(2-{[1-Methoxycarbonyl-1-phenyl-meth-(Z)-ylidene]-hydrazono}-1-methyl-propylidene)-[1,3]dithietan-2-ylidene]-1-methyl-prop-(Z)-ylidene]-hydrazono}-phenyl-acetic acid methyl ester (107798-24-3) + trans-5,10-bis(methoxycarbonyl)-5,10-diphenylpyrazolo<1,5-a:1',5'-e><1,5>diaza<3,6>dithiocine (107769-87-9)

Guidance literature:

at 140 ℃; for 1.5h;

DOI:10.1021/jo00385a029

Reference yield:

methyl 2-oxo-2-phenylacetate (15206-55-0) → {[2-[4-(2-{[1-Methoxycarbonyl-1-phenyl-meth-(Z)-ylidene]-hydrazono}-1-methyl-propylidene)-[1,3]dithietan-2-ylidene]-1-methyl-prop-(Z)-ylidene]-hydrazono}-phenyl-acetic acid methyl ester (107798-24-3)

Guidance literature:

Multi-step reaction with 6 steps

1: 53 percent / aq. hydrazine, aq. HCl / methanol / 96 h / Ambient temperature

2: 75 percent / CH₂Cl₂ / 4 h / Heating

3: 85 percent / KOH / methanol / 0.5 h / -5 °C

4: 83 percent / acetonitrile / 0.5 h / Heating

5: 86 percent / NaOMe / methanol / 0.5 h / 0 °C

6: 9 percent / 1.5 h / 140 °C

With hydrogenchloride; potassium hydroxide; sodium methylate; hydrazine hydrate; In methanol; dichloromethane; acetonitrile;

DOI:10.1021/jo00385a029

Reference yield:

methyl α-hydrazonophenylacetate (23102-11-6) → {[2-[4-(2-{[1-Methoxycarbonyl-1-phenyl-meth-(Z)-ylidene]-hydrazono}-1-methyl-propylidene)-[1,3]dithietan-2-ylidene]-1-methyl-prop-(Z)-ylidene]-hydrazono}-phenyl-acetic acid methyl ester (107798-24-3)

Guidance literature:

Multi-step reaction with 5 steps

1: 75 percent / CH₂Cl₂ / 4 h / Heating

2: 85 percent / KOH / methanol / 0.5 h / -5 °C

3: 83 percent / acetonitrile / 0.5 h / Heating

4: 86 percent / NaOMe / methanol / 0.5 h / 0 °C

5: 9 percent / 1.5 h / 140 °C

With potassium hydroxide; sodium methylate; In methanol; dichloromethane; acetonitrile;

DOI:10.1021/jo00385a029

upstream raw materials:

carbon disulfide

triphenyl<1-methyl-2-((phenyl(methoxycarbonyl)methylene)hydrazono)propylidene>phosphorane

methyl 2-oxo-2-phenylacetate

methyl α-hydrazonophenylacetate