Technology Process of 2-<(phenylthio)carbonyl>tetrahydropyran
There total 6 articles about 2-<(phenylthio)carbonyl>tetrahydropyran which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
(1,2-dimethoxyethane)dichloronickel(II); Ir[2-(2,4-difluorophenyl)-5-(trifluoromethyl)pyridine]2(4,4'-di-tert-butyl-2,2'-bipyridine)PF6; potassium carbonate; 1,3-bis[(2,6-diisopropyl)phenyl]imidazolinium chloride;
at 20 ℃;
for 12h;
chemoselective reaction;
Irradiation;
DOI:10.1039/c7sc02516e
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) potassium tert-butoxide / 1.) tert-butyl alcohol, THF, 0 deg C, 15 min, 2.) tert-butyl alcohol, THF, RT
2: methanesulfonyl chloride, ethyldiisopropylamine / CH2Cl2 / 1.) -78 deg C, 10 min, 2.) -30 deg C, 10 min
3: 90 percent / HF*pyridine / CH2Cl2 / 0.5 h / -78 °C
4: 1.) potassium tert-butoxide, 2.) ozone / 1.) THF, tert-butyl alcohol, -78 deg C, 15 min, 2.) THF, tert-butyl alcohol, CH2Cl2
With
potassium tert-butylate; pyridine hydrogenfluoride; ozone; methanesulfonyl chloride; N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
DOI:10.1021/jo00280a058
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) potassium tert-butoxide / 1.) tert-butyl alcohol, THF, 0 deg C, 15 min, 2.) tert-butyl alcohol, THF, RT
2: methanesulfonyl chloride, ethyldiisopropylamine / CH2Cl2 / 1.) -78 deg C, 10 min, 2.) -30 deg C, 10 min
3: 90 percent / HF*pyridine / CH2Cl2 / 0.5 h / -78 °C
4: 1.) potassium tert-butoxide, 2.) ozone / 1.) THF, tert-butyl alcohol, -78 deg C, 15 min, 2.) THF, tert-butyl alcohol, CH2Cl2
With
potassium tert-butylate; pyridine hydrogenfluoride; ozone; methanesulfonyl chloride; N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
DOI:10.1021/jo00280a058
